Daily Journal Digest — 2026-06-23¶
過去 24 小時新增：Transplant ID × 26、One Health × 15、Food Security × 14，共 55 篇。
⭐ 今日亮點¶
- Andes virus-associated cardiopulmonary syndrome: diagnostic approaches, clinical management, and evidence gaps-a scoping review
高致死zoonosis的診斷與升級照護地圖。 - One Health genomics reveals niche-specific lineage replacement in Salmonella Enteritidis
把One Health與AMR演化串成可行動監測框架。 - Confronting the known unknown: historical lessons and future strategies for Disease X
以Nipah再起為鏡，提出Disease X的One Health監測—診斷—治療連續體框架。
🔬 深入評讀¶
Andes virus-associated cardiopulmonary syndrome: diagnostic approaches, clinical management, and evidence gaps-a scoping review¶
Clin Microbiol Infect | IF 8.0 | DOI | [(Fama2026Andesvirusassociated?)]
- 設計：這是scoping review，搜尋PubMed/MEDLINE、Embase、Scopus、Cochrane Library與ClinicalTrials.gov共5個資料庫，涵蓋1993-01-01至2026-05-13的ANDV-HCPS臨床文獻。它把診斷、支持性治療、ECMO、antiviral與immune plasma等問題整理成1個臨床管理框架。
- 樣本：共納入40篇研究，多數來自智利與阿根廷，研究型態以retrospective cohorts、case series與case reports為主。可用證據幾乎沒有randomized trial，追蹤資料也以急性住院期為主，長期post-discharge morbidity資料明顯不足。
- 關鍵數字：診斷上serology是常規主力，RT-PCR多用於診斷困難個案，且0個validated ANDV-specific point-of-care test；治療上仍是mechanical ventilation、vasopressors與ECMO等支持性照護。ECMO在specialist centres與較佳存活相關，但效應量來自觀察性資料，代表訊號重要卻不夠穩健。
- Limitation：40篇研究多為回溯與個案報告，selection bias、referral bias與survivor bias都可能放大ECMO等高階照護的表面效益。診斷標準、嚴重度分層與升級照護門檻未在各研究間一致化，讓跨研究比較至少有3層異質性。
- Bottom line：ANDV-HCPS應被視為可跨境擴散的高致死One Health急症，臨床重點是早期serology/RT-PCR路徑、明確升級照護標準，以及把重症個案快速轉到具ECMO經驗的中心。
One Health genomics reveals niche-specific lineage replacement in Salmonella Enteritidis¶
Natl Sci Rev | DOI | [(Zhou2026OneHealth?)]
- 設計：這是全國尺度的One Health genomics研究，整合中國人類、動物、食品與環境4個界面的S. Enteritidis isolates。分析重點是20年間lineage dynamics、mobile genetic elements、stress tolerance、metabolic plasticity與human-centric dissemination。
- 樣本：摘要未揭露總isolate數，但明確指出這是中國目前最大S. Enteritidis genomic資料集，涵蓋20年與至少4個來源界面。比較組不是傳統2組臨床cohort，而是Global-b1、Global-b2與Global-c共3個主要lineages的時序與生態位比較。
- 關鍵數字：核心發現是MDR率在20年間增加3倍，且Global-c透過resistance-driven lineage replacement取得比例優勢。這個效應不是小幅漂移，而是AMR、mobile genetic elements與環境適應共同推動的lineage replacement，對公共衛生監測的訊號相當大。
- Limitation：基因體監測受sampling frame影響很大，4個界面的採樣密度若不均，可能把監測偏差誤認為lineage replacement。SNP-distance mapping可提示human-centric dissemination，但不能單獨證明傳播方向，也缺少與臨床嚴重度或治療失敗直接連結的數字。
- Bottom line：對AMR監測來說，S. Enteritidis不能只看serovar或單株AST，應把lineage、mobile genetic elements與跨界面傳播納入One Health surveillance。
Confronting the known unknown: historical lessons and future strategies for Disease X¶
Front Public Health | DOI | [(Xiang2026Confrontingknown?)]
- 設計：這是一篇敘事型綜論（narrative review，evidence level：專家綜整），以 2026 年印度西孟加拉 Nipah virus（WHO priority pathogen）疫情為引，論述對「Disease X」（未知病原引發的未來大流行）的防備缺口，並提出整合式應對框架。屬非系統性回顧，未預先註冊搜尋策略或納入流程。
- 範圍：論述主軸是 COVID-19 的經驗教訓，橫跨人類、動物與環境 3 個介面（One Health）；無量化文獻合成，亦未報告納入篇數、效應量或統計檢定。
- 核心主張：提出一條「One Health surveillance–diagnostic–therapeutic continuum」——即時病原追蹤＋宿主免疫 profiling，據以適時啟動 non-pharmaceutical interventions、動態建模與精準投放 rapid medical countermeasures；並強調韌性醫療基礎建設、公平的資料共享，以及重視全球協作與公平的治理模式。
- Limitation：屬意見／框架型綜論，未做系統性搜尋與證據分級，論點以專家綜整為主、缺乏量化證據支撐各環節成效；所提 continuum 為概念框架，尚未經實證驗證，落地成本、治理與跨國資料共享的可行性未深入評估；發表於非旗艦 OA 期刊（Front Public Health）。
- Bottom line：價值在框架性提醒而非新數據——Disease X 防備應被操作化為跨介面、即時的監測—診斷—治療連續體，並配套公平的資料治理；Nipah 再起提醒，這類高致死新興病原是現在進行式而非未來式。
🔴 Transplant & Opportunistic Infections¶
Clinical characteristics, opportunistic infection spectrum and epidemiological analysis of pediatric AIDS patients in southwest China¶
Authors: Liao Y et al. | Journal: Front Cell Infect Microbiol | Date: 2026
DOI: 10.3389/fcimb.2026.1824149
TL;DR: 中國西南87名住院兒童HIV/AIDS以母嬰傳播為主，candidiasis 45.3%、tuberculosis 26.7%；70% CD4+T下降，93.1%好轉出院。
嘻嘻：小兒HIV照護還有路，但出院結局先給人一點氣。
Comorbidities, health-related quality of life and its associated factors among people living with HIV/AIDS in Gandaki Province of Nepal¶
Authors: Paudel S et al. | Journal: BMC Public Health | Date: 2026 Jun 20
DOI: 10.1186/s12889-026-28192-5
TL;DR: 尼泊爾337名PLHIV中52.2% HRQoL不佳、28.2%有共病；共病者HRQoL不佳勝算較高（AOR 1.65，95% CI 0.98–2.78）。
不嘻嘻：HIV活得久了，共病也準時來加班。
Performance of ultra-sensitive electrochemiluminescence LAM assay for diagnosing tuberculosis in HIV-negative individuals: a multicentre, prospective diagnostic study¶
Authors: Shang Y et al. | Journal: Infection | Date: 2026 Jun 22
DOI: 10.1007/s15010-026-02861-4
TL;DR: 北京692名HIV陰性疑似pulmonary TB成人中，AIMLAM對MRS敏感度61.6%、特異度83.0%；對CRS特異度達98.0%。
嘻嘻：LAM變敏銳了，TB診斷工具箱總算多一把。
Is There Value in Performing Yearly Screening for Latent Tuberculosis Infection by Interferon-Gamma Release Assay Among Patients Living With HIV in Non-Endemic Settings?¶
Authors: Foppiano Palacios C et al. | Journal: Open Forum Infect Dis | Date: 2026 Jun
DOI: 10.1093/ofid/ofag227
TL;DR: 非endemic地區1898名HIV感染者5年年度IGRA篩檢僅12例新LTBI，普篩效益低，結果支持依現行指引採風險導向篩檢。
不嘻嘻：年年篩像報稅，低風險族群真的不用硬刷存在感。
Review: natural compounds as PCSK9 inhibitors for antiviral therapy¶
Authors: Kareem RA et al. | Journal: Arch Microbiol | Date: 2026 Jun 22
DOI: 10.1007/s00203-026-05006-1
TL;DR: PCSK9與HIV、SARS-CoV-2、DENV、hepatitis viruses相關；curcumin等天然物多停留於in vitro與動物證據，尚非臨床抗病毒替代療法。
不嘻嘻：curcumin又來應徵萬用藥，先請它通過臨床再說。
Cold agglutinin syndrome secondary to Epstein-Barr virus reactivation during corticosteroid therapy for minimal change nephrotic syndrome in a patient with human immunodeficiency virus infection¶
Authors: Bamba H et al. | Journal: CEN Case Rep | Date: 2026 Jun 22
DOI: 10.1007/s13730-026-01145-y
TL;DR: 63歲HIV控制良好患者因minimal change nephrotic syndrome用prednisolone 80 mg/day後EBV reactivation併cold agglutinin syndrome，減量與支持治療後改善。
嘻嘻：HIV穩定也會出奇招，這例提醒很實用。
Balancing the Game: The Relationship of Lower-Limb Asymmetry With Youth Soccer (Football) Performance - Laboratory vs. Field Insights¶
Authors: Bartusevičius D et al. | Journal: J Strength Cond Res | Date: 2026 Jun 22
DOI: 10.1519/JSC.0000000000005570
TL;DR: 29名青少年足球員中，實驗室與場地LSI相關低，且與體能、BKV關聯有限；BKV與CMJ呈大型正相關（r 0.531–0.572）。
不嘻嘻：實驗室很努力，球場表示先不要太相信它。
Risk Factors and Prediction of Chronic Obstructive Pulmonary Disease After Pulmonary Tuberculosis: A Prospective Cohort Study¶
Authors: Ye X et al. | Journal: Int J Chron Obstruct Pulmon Dis | Date: 2026
DOI: 10.2147/COPD.S594436
TL;DR: 湖南324名PTB治癒者追蹤至2025年，83人（25.6%）發生COPD；7變項模型AUC 0.806，bootstrap校正C-index 0.787。
不嘻嘻：TB好了不代表肺沒事，後續帳單才剛寄到。
Severe Pulmonary Coccidioidomycosis Treated With Systemic Corticosteroids in an Adolescent Child¶
Authors: Shinozaki R et al. | Journal: Case Rep Pediatr | Date: 2026
DOI: 10.1155/crpe/6010113
TL;DR: 18歲腎移植免疫低下患者發生severe pulmonary coccidioidomycosis併ARDS；在標準antifungals加systemic corticosteroids後臨床改善。
嘻嘻：coccidioidomycosis重症能拉回來，案例有點振奮。
HIV-Associated Pulmonary Arterial Hypertension in Resource-Limited Settings: A "Forgotten" Diagnosis, a Great Imitator, and a Multi-Hit Pulmonary Vasculopathy¶
Authors: Eroume A Egom E et al. | Journal: Pulm Circ | Date: 2026 Jun
DOI: 10.1002/pul2.70341
TL;DR: HIV-PAH高收入國家catheter-confirmed盛行率約0.5%，法國研究0.46%；資源有限地區常被TB肺病、anemia等掩蓋，需echo導向早期辨識。
不嘻嘻：HIV-PAH太會偽裝，臨床眼睛又要更利。
LAMP-Based Detection of Candida albicans: A Potential Tool for Candidemia Diagnosis¶
Authors: Prompunt E et al. | Journal: Can J Infect Dis Med Microbiol | Date: 2026
DOI: 10.1155/cjid/1980977
TL;DR: ITS2-targeted LAMP可偵測C. albicans DNA低至10 fg，優於conventional PCR 10 pg；spiked blood中可偵測101 CFU/mL且無交叉反應。
嘻嘻：C. albicans快篩若能落地，candidemia會少等很多。
Severely reduced antioxidant and impaired mitochondrial biomarkers could be linked to post-tuberculosis lung disease in a cohort from South Africa¶
Authors: Payne C et al. | Journal: Afr J Thorac Crit Care Med | Date: 2026
DOI: 10.7196/AJTCCM.2026.v32i1.2827
TL;DR: 南非post-TB患者serum顯示metallothionein-1低240倍、catalase低7.5倍、SOD低273倍，提示PTLD可能與抗氧化與mitochondrial pathways受損相關。
不嘻嘻：post-TB肺病像長尾帳，粒線體也被拖下水。
Nontuberculosis Mycobacterial Infections: A Series of 14 Cases from a Tertiary Care Center in Türkiye¶
Authors: Ertürk D et al. | Journal: Infect Dis Clin Microbiol | Date: 2026 May
DOI: 10.36519/idcm.2026.953
TL;DR: 土耳其14例NTM感染以M. kansasii與M. abscessus各5例最多；12人治療中9人完全反應，2名malignancy患者治療前死亡。
嘻嘻：NTM雖難搞，治療反應還算給面子。
Lipid Flippase Mediated Membrane Asymmetry Governs Extracellular Vesicles Biogenesis and Host Interactions in Cryptococcus neoformans¶
Authors: Pawar S et al. | Journal: bioRxiv | Date: 2026 Jun 12
DOI: 10.64898/2026.06.12.731820
TL;DR: C. neoformans Cdc50缺失造成phospholipid-rich EV過度產生、增強macrophage phagocytosis，並因phagosome acidification而較易被殺死。
嘻嘻：C. neoformans被膜翻面後，免疫系統終於抓到破綻。
TREM2 drives monocyte-derived macrophage responses to Cryptococcus neoformans¶
Authors: Abass A et al. | Journal: bioRxiv | Date: 2026 Jun 11
DOI: 10.64898/2026.06.10.731331
TL;DR: TREM2在小鼠肺部monocytes與interstitial macrophages受C. neoformans誘導，經DAP12抑制fungal uptake與M1 polarization，且可直接結合β-1,6-glucan相關結構。
嘻嘻：TREM2這條線，讓cryptococcosis免疫劇情更好看。
Structural Cardiac Abnormalities, Ventricular Dysfunction Phenotypes, and Heart Failure Risk among Antiretroviral Therapy-treated People Living with HIV in South Africa¶
Authors: Omar Z et al. | Journal: medRxiv | Date: 2026 Jun 08
DOI: 10.64898/2026.06.04.26354960
TL;DR: 南非1008名ART-treated PWH與500名對照中HF頻率10%、HFpEF 8%；PWH較易LVMI升高（OR 2.1）與DD（OR 1.4），女性風險最高。
不嘻嘻：ART救了命，心臟共病也默默排隊報到。
Within-household transmission risk of pulmonary tuberculosis in the era of universal antiretroviral therapy¶
Authors: Khan PY et al. | Journal: medRxiv | Date: 2026 Jun 09
DOI: 10.64898/2026.06.01.26354571
TL;DR: 南非296名pulmonary TB index cases與755名兒童接觸者中，有效ART未降低家戶MTBC傳播（RR 1.07）；無咳嗽者風險較低（RR 0.61）。
不嘻嘻：ART很重要，但家戶TB傳播不會因此自動下班。
Bacterial topography of the respiratory tract, including pulmonary site-of-disease, in people with active tuberculosis: a case-control study¶
Authors: Chiyaka TL et al. | Journal: Res Sq | Date: 2026 Jun 09
DOI: 10.21203/rs.3.rs-9956587/v1
TL;DR: 17名HIV陰性TB患者與11名對照的16S分析顯示，LRT α-diversity最低；病灶肺葉Mycobacterium相對豐度1.537%，痰僅0.002%。
嘻嘻：肺內細菌地圖打開後，痰液真的不再全知全能。
Serological and biochemical characterization of Aspergillus fumigatus Asp f 10 as a potential diagnostic marker in ABPA and related respiratory diseases¶
Authors: Ghosh S et al. | Journal: Front Allergy | Date: 2026
DOI: 10.3389/falgy.2026.1733299
TL;DR: A. fumigatus Asp f 10-specific IgG可區分ABPA與相關疾病，ROC AUC 0.90，明顯優於IgE AUC 0.54；成熟蛋白雖被IgE辨識但未誘發histamine release。
嘻嘻：Asp f 10看起來很會分辨ABPA，值得追。
Vitamin D-AMP axis in host defense against fungal infections¶
Authors: Akimbekov NS et al. | Journal: Front Nutr | Date: 2026
DOI: 10.3389/fnut.2026.1807743
TL;DR: Vitamin D可調節AMPs對Candida、Aspergillus、Cryptococcus等真菌的host defense；直接以vitamin D3抗真菌受限於高劑量與高鈣風險。
不嘻嘻：vitamin D聽起來萬能，高鈣風險馬上提醒別衝動。
Uncovering the Predisposing Factors of Mucormycosis: Insights from Systematic Review¶
Authors: Ravindhiran R et al. | Journal: Indian J Microbiol | Date: 2026 Jun
DOI: 10.1007/s12088-025-01491-y
TL;DR: 系統性回顧指出mucormycosis風險因地區不同：已開發國家以hematological malignancies為主，印度等地以未控制diabetes mellitus為主，延遲診斷仍致高死亡。
不嘻嘻：mucormycosis還是那句老話：慢一步就很貴。
Breakthrough Tracheobronchial Aspergillosis Caused by Aspergillus calidoustus and Aspergillus niger in a Lung Transplant Recipient Despite Combined Antifungal Prophylaxis¶
Authors: Calvache Benavides CE et al. | Journal: Case Rep Pulmonol | Date: 2026
DOI: 10.1155/crpu/7415627
TL;DR: 61歲單肺移植患者在voriconazole預防下仍發生tracheobronchial aspergillosis，病原為A. niger與A. calidoustus，凸顯molecular identification必要性。
不嘻嘻：預防用藥都上了，Aspergillus還是硬闖門。
Molecular Characterization and Antifungal Profiling of Nine Phenotypic Aspergillus nidulans Isolates: A Case Series From North India¶
Authors: Nikhil A et al. | Journal: Microbiologyopen | Date: 2026 Jun
DOI: 10.1002/mbo3.70338
TL;DR: 北印度9株表型A. nidulans經ITS定序後僅2株為A. nidulans，5株為A. stellatus；A. stellatus amphotericin B MIC較高（2 µg/mL）。
不嘻嘻：長得像不等於是，黴菌命名又來考驗耐心。
Risk Factors and Survival Analysis of Epstein-Barr Virus Infection After Pediatric Liver Transplantation¶
Authors: Li Y et al. | Journal: Pediatr Int | Date: 2026
DOI: 10.1111/ped.70431
TL;DR: 四川251名兒童肝移植後EBV感染常見；tacrolimus trough、術前EBV感染與移植年齡為獨立風險因子，5年存活率與未感染組無顯著差異（p=0.376）。
嘻嘻：EBV雖常見，存活率沒被拖垮算好消息。
STAT2-IRF1-ISG15-Associated Temporal Immune Reprogramming in Macrophages during Aspergillus fumigatus Infection¶
Authors: Zhou Q et al. | Journal: Curr Microbiol | Date: 2026 Jun 20
DOI: 10.1007/s00284-026-05017-7
TL;DR: A. fumigatus刺激human macrophages後DEGs於8小時達高峰；STAT2 2小時、IRF1 4小時、ISG15至8小時持續升高，提示STAT2-IRF1-ISG15時序反應。
嘻嘻：A. fumigatus免疫時鐘被拆開，機制派今天有料。
Path beyond the blind end-unravel the imaging spectrum of appendiceal pathologies¶
Authors: Konduru SKP et al. | Journal: Abdom Radiol (NY) | Date: 2026 Jun 20
DOI: 10.1007/s00261-026-05608-9
TL;DR: 影像綜論整理appendix發炎、感染、良惡性腫瘤與mimics的US、CT、MRI特徵，強調影像在鑑別診斷、分期與治療規劃的角色。
嘻嘻：appendix影像再整理一次，急診夜班會感謝。
🟢 One Health / Zoonoses¶
Andes virus-associated cardiopulmonary syndrome: diagnostic approaches, clinical management, and evidence gaps-a scoping review¶
Authors: Fama F et al. | Journal: Clin Microbiol Infect | Date: 2026 Jun 20
DOI: 10.1016/j.cmi.2026.06.013
TL;DR: ANDV-HCPS scoping review納入40篇，多為智利與阿根廷回溯cohort或case reports；診斷以serology為主，治療仍支持性，ECMO證據限觀察性。
不嘻嘻：ANDV-HCPS治療仍靠支持，證據荒很有既視感。
A One Health investigation of a Crimean-Congo Hemorrhagic fever outbreak reveals high seropositivity in livestock in Lyantonde District, Uganda, 2024¶
Authors: Nyakarahuka L et al. | Journal: One Health | Date: 2026 Dec
DOI: 10.1016/j.onehlt.2026.101470
TL;DR: 烏干達Lyantonde 2024年CCHF outbreak確認5例人類病例，皆有牲畜接觸；26隻山羊中88% CCHFV IgG陽性、PCR陰性，病毒屬Africa II clade。
不嘻嘻：CCHF提醒我們，牲畜端永遠不能裝沒看到。
Rapid serological detection of smooth Brucella strain antibodies in bovine and sheep using a dynamic flow immunochromatographic test¶
Authors: Zhou K et al. | Journal: Front Cell Infect Microbiol | Date: 2026
DOI: 10.3389/fcimb.2026.1804374
TL;DR: DFICT用於牛羊Smooth brucellosis血清抗體，10分鐘肉眼判讀；臨床驗證牛敏感度94.6%、特異度100%，羊敏感度98.2%、特異度84.0%。
嘻嘻：brucellosis十分鐘判讀，現場篩檢有點香。
Epidemiological analysis of infectious disease in border port areas of Heilongjiang Province, 2014-2023¶
Authors: Wei ST et al. | Journal: BMC Public Health | Date: 2026 Jun 20
DOI: 10.1186/s12889-026-27942-9
TL;DR: 黑龍江18個邊境口岸2014–2023年通報64,865例法定傳染病，年均220.30/10萬；pulmonary TB占23.56%，呼吸道疾病AAPC 6.61%上升。
不嘻嘻：邊境呼吸道病上升，監測人員又少睡一點。
Designing of a conserved subunit multiepitope vaccine candidate against Francisella tularensis Schu S4 using immunoinformatics¶
Authors: Ahmed SS et al. | Journal: Sci Rep | Date: 2026 Jun 20
DOI: 10.1038/s41598-026-58834-y
TL;DR: 針對F. tularensis Schu S4的TulaVac1/2以immunoinformatics設計，MHC I/II全球涵蓋率73.19%與99.74%，200 ns MD顯示穩定交互作用。
嘻嘻：F. tularensis疫苗設計先過電腦關，值得期待。
Long-read metagenomics reveals stable resistome and microbiome in treated Italian slaughterhouse wastewater: a preliminary study¶
Authors: Pallotti S et al. | Journal: Microbiol Spectr | Date: 2026 Jun 22
DOI: 10.1128/spectrum.01562-26
TL;DR: 義大利4家屠宰場廢水long-read metagenomics找到96個ARG、涵蓋16類抗生素；coagulation-flocculation處理前後microbiome與resistome無顯著改變。
不嘻嘻：廢水處理後抗藥基因沒退場，環境帳很難結。
Validation of a duplex real-time PCR (qPCR) in clinically classified dogs naturally infected with Leishmania infantum before and after specific treatment: preliminary results¶
Authors: Gómez-Velasco C et al. | Journal: Parasit Vectors | Date: 2026 Jun 21
DOI: 10.1186/s13071-026-07490-2
TL;DR: 66隻犬leishmaniosis樣本中，lymph node PCR敏感度與parasite load最高；oral swab為最佳非侵入樣本，qPCR LoD 0.5 parasite equivalents/reaction。
嘻嘻：犬隻leishmaniosis能用oral swab追，毛孩也少受苦。
Confronting the known unknown: historical lessons and future strategies for Disease X¶
Authors: Xiang Y et al. | Journal: Front Public Health | Date: 2026
DOI: 10.3389/fpubh.2026.1833807
TL;DR: 以2026年印度西孟加拉Nipah outbreak為例，綜論主張Disease X需One Health surveillance-diagnostic-therapeutic continuum，串接pathogen tracking、免疫profiling與快速醫療對策。
不嘻嘻：Disease X聽起來未來，其實永遠在門口等。
High prevalence and cross-species transmission potential of Entamoeba gingivalis and Trichomonas tenax in humans, dogs, and cats in Guangxi, China¶
Authors: Luo B et al. | Journal: Acta Trop | Date: 2026 Jun 21
DOI: 10.1016/j.actatropica.2026.108198
TL;DR: 廣西93人、298犬、325貓口腔拭子中，E. gingivalis盛行率皆>90%；T. tenax在犬25.17%、貓16.62%、人4.30%，犬感染與老年、periodontal disease相關。
不嘻嘻：口腔原蟲跨物種串門，牙周門診也有One Health。
First Molecular Detection of Infectious Spleen and Kidney Necrosis Virus (ISKNV) and the Parasite Centrocestus formosanus in the Ornamental Fish Platy (Xiphophorus maculatus) in Chile¶
Authors: Solano-Iguaran JJ et al. | Journal: J Fish Dis | Date: 2026 Jun 21
DOI: 10.1111/jfd.70223
TL;DR: 智利13處檢疫設施、24種觀賞魚中，platy fish首次分子偵測到ISKNV；2尾ISKNV陽性魚鰓部也檢出C. formosanus metacercariae。
不嘻嘻：觀賞魚也能帶貨，檢疫真的不能只看可愛。
Epidemiology and Control of Foodborne Diseases in Resource-Limited Settings: Insights from Afghanistan¶
Authors: Zahir A et al. | Journal: J Food Prot | Date: 2026 Jun 20
DOI: 10.1016/j.jfp.2026.100843
TL;DR: 以阿富汗為例的綜論指出，資源有限地區FBDs主要受不安全用水、非正式市場與衛生不良驅動，常見污染含E. coli、Salmonella spp.與寄生蟲。
不嘻嘻：食媒疾病的老敵人，還是水、衛生與貧窮。
One Health genomics reveals niche-specific lineage replacement in Salmonella Enteritidis¶
Authors: Zhou H et al. | Journal: Natl Sci Rev | Date: 2026 Jun
DOI: 10.1093/nsr/nwag275
TL;DR: 中國最大S. Enteritidis genomic資料顯示，20年間MDR率增加3倍；Global-c lineage透過resistance-driven lineage replacement取得比例優勢，並有human-centric dissemination訊號。
不嘻嘻：S. Enteritidis抗藥性加速換班，雞蛋更不單純了。
A comprehensive review of bacterial and hemoparasitic diseases in the water buffalo¶
Authors: Barrios-García HB et al. | Journal: Front Vet Sci | Date: 2026
DOI: 10.3389/fvets.2026.1812517
TL;DR: 系統性回顧180篇顯示水牛雖臨床疾病死亡率低，仍可作為brucellosis、tuberculosis、leptospirosis、salmonellosis與hemoparasites reservoir。
不嘻嘻：水牛很淡定，病原卻可能搭便車很忙。
Animal-human interfaces and emerging zoonoses: Salmonella in pet turtles in Concepción, Chile¶
Authors: Faundez F et al. | Journal: Front Vet Sci | Date: 2026
DOI: 10.3389/fvets.2026.1783800
TL;DR: 智利康塞普西翁72隻寵物紅耳龜179件樣本中，42隻（58.3%）檢出Salmonella；shell swab陽性率30.6%，提示直接fomite傳播風險。
不嘻嘻：寵物龜摸起來療癒，Salmonella可不療癒。
Culture-enriched sequencing reveals river confluence sediments as high-risk reservoirs of viable multidrug-resistant pathogens¶
Authors: Li Y et al. | Journal: J Hazard Mater | Date: 2026 Jun 19
DOI: 10.1016/j.jhazmat.2026.142756
TL;DR: 汾河-黃河匯流沉積物培養富集後121株分離株中94.2%具抗藥性、73.5%為MDR；另得7株高風險MDR pathogens，含Pseudomonas、Acinetobacter、Aeromonas。
不嘻嘻：河流沉積物變MDR倉庫，環境微生物很會囤貨。
🟡 Food Security / Food Safety¶
A contribution to the improvement of Listeria monocytogenes enumeration at low level of contamination, in the frame of the international standardization¶
Authors: Gnanou Besse N et al. | Journal: Int J Food Microbiol | Date: 2026 Jun 16
DOI: 10.1016/j.ijfoodmicro.2026.111913
TL;DR: EURL Lm與NRLs評估2種由ISO 11290-2衍生的低量L. monocytogenes計數法，聚焦practicability、relative trueness、repeatability與accuracy profile。
嘻嘻：低量L. monocytogenes計數更準，食品安全少一點猜。
Insights in Food Allergy from DCs: The Influence and Mechanism of Diet Components with Antiallergic Properties¶
Authors: Li L et al. | Journal: J Agric Food Chem | Date: 2026 Jun 22
DOI: 10.1021/acs.jafc.6c04034
TL;DR: 食物過敏綜論聚焦dietary components-DCs-FA axis，說明vitamins、fatty acids、polyphenols、dietary fiber與probiotics如何調節DCs並影響tolerance或allergic responses。
嘻嘻：飲食調DCs這條路，食物過敏研究很有戲。
Determinants of out-of-home food consumption: development and validation of a multidimensional scale in a Brazilian sample¶
Authors: Lopes LFD et al. | Journal: BMC Public Health | Date: 2026 Jun 22
DOI: 10.1186/s12889-026-28251-x
TL;DR: 巴西426名成人驗證SDF-OHFC五構面量表，Cronbach’s α 0.705–0.762、AVE>0.50；經濟因素正向影響便利與習慣，負向影響社交體驗。
嘻嘻：外食動機被量化，公共衛生終於有尺可量。
Phenotypic detection of ESBL, AmpC, and carbapenemase-producing Enterobacteriaceae from retail fresh vegetables in Iwo, Nigeria¶
Authors: Akinola OT et al. | Journal: BMC Microbiol | Date: 2026 Jun 20
DOI: 10.1186/s12866-026-05139-9
TL;DR: 奈及利亞Iwo 50件新鮮蔬菜分離46株腸道菌，含K. pneumoniae 52%、K. aerogenes 22%；所有分離株對測試β-lactams皆100%抗藥。
不嘻嘻：生菜配β-lactam抗藥菌，沙拉瞬間不清爽。
A new and eco-friendly disinfectant for antimicrobial-resistant bacteria: ozone nano water¶
Authors: Wang W et al. | Journal: BMC Microbiol | Date: 2026 Jun 20
DOI: 10.1186/s12866-026-05120-6
TL;DR: ONW可快速殺滅4株E. coli（含3株MDR clinical isolates）並抑制biofilm；連續3代未顯著改變抗生素敏感性，作用涉及多靶點氧化傷害。
嘻嘻：ozone nano water若真穩，消毒界會想加菜。
A single amino acid in the viral capsid makes a major contribution to the interaction between human norovirus GII.6 and the bacterial Psl exopolysaccharide¶
Authors: Li X et al. | Journal: Appl Environ Microbiol | Date: 2026 Jun 22
DOI: 10.1128/aem.02282-25
TL;DR: Human norovirus GII.6 capsid P domain B loop的V297決定與Pseudomonas-derived Psl EPS結合，且GII.6結合力顯著強於GII.4，解釋食物與環境中持續性。
嘻嘻：norovirus黏菌膠的關鍵位點抓到了，環境持續性更清楚。
Identifying hot-spot pathways in fishery science and technology innovation through temporal heterogeneous graph neural networks¶
Authors: Zhang F et al. | Journal: Sci Rep | Date: 2026 Jun 21
DOI: 10.1038/s41598-026-58675-9
TL;DR: DTH-GNN整合2010–2024年32,847篇文獻、8,956件專利與1,856項計畫，預測fishery S&T hot-spot pathways達AUC 0.934、AP 0.928。
嘻嘻：GNN拿來看漁業創新熱點，跨域工具感很強。
USP Gene Network Modulation and Osmoprotection Define Salt Resilience in Chenopodium quinoa Genotypes¶
Authors: Imran H et al. | Journal: Sci Rep | Date: 2026 Jun 21
DOI: 10.1038/s41598-026-57595-y
TL;DR: 8個quinoa品系鹽逆境分析顯示，Q-33最具resilience；耐鹽仰賴osmolytes誘導、photoprotection、ROS scavenging與USP gene network動態調控。
嘻嘻：quinoa抗鹽機制拆得細，作物韌性研究有進展。
Enhancing Consumer Acceptance of Cricket (Acheta domesticus) Protein Hydrolysate Through ProteAX-Mediated Enzymatic Hydrolysis to Improve Techno-Functional and Organoleptic Properties¶
Authors: Fetriyuna F et al. | Journal: Food Sci Nutr | Date: 2026 Jun
DOI: 10.1002/fsn3.72033
TL;DR: cricket protein以ProteAX 1.5%、5小時水解達67.71% degree of hydrolysis、蛋白69.51%、溶解度98.99%，苦味低且umami較強。
嘻嘻：cricket protein變好入口，未來蛋白少一點心理障礙。
Molecular characterization of thioredoxin peroxidases 1 from Trichinella spiralis and its potential in generating protective immunity¶
Authors: Tong M et al. | Journal: Parasit Vectors | Date: 2026 Jun 20
DOI: 10.1186/s13071-026-07517-8
TL;DR: rTs-TPx1加ISA206免疫小鼠後誘發Th2偏向混合Th1/Th2反應，口服挑戰T. spiralis後adult worm burden降65.0%、muscle larval burden降61.8%。
嘻嘻：T. spiralis疫苗保護力不差，寄生蟲也被逼退一步。
cMicrobial Food Safety Risk in Finished Soil Amendment: A Statewide Cross-sectional Study of Organic Waste Processing Systems in California¶
Authors: Nie K et al. | Journal: J Food Prot | Date: 2026 Jun 20
DOI: 10.1016/j.jfp.2026.100844
TL;DR: 加州35處有機廢棄物處理場184件finished soil amendments中，註冊設施75/108（69.4%）符合fecal coliform限值且未檢出STEC、Salmonella或L. monocytogenes。
嘻嘻：土壤改良物過關率還行，堆肥終點不是盲盒。
Epitope-Imprinted Polymers for Selective Recognition of Bacterial Proteins: From Design to Analytical Applications¶
Authors: El-Tahlawy AS et al. | Journal: ACS Meas Sci Au | Date: 2026 Jun 17
DOI: 10.1021/acsmeasuresciau.6c00055
TL;DR: EIPs以細菌表面蛋白epitope建立穩定辨識腔，可偵測M. leprae、Salmonella Typhi與N. meningitidis；仍受matrix interference與量產再現性限制。
嘻嘻：EIPs像人工抗體，細菌蛋白偵測多一條路。
Development of Recombinase Polymerase Amplification Assay for the Rapid Detection of Salmonella Serovars from Food Samples¶
Authors: Padavu S et al. | Journal: Indian J Microbiol | Date: 2026 Jun
DOI: 10.1007/s12088-025-01514-8
TL;DR: 針對Salmonella enterica的RPA可在20分鐘完成、偵測極限55 fg DNA，反應溫度低於傳統PCR，適合food samples現場快速篩檢。
嘻嘻：Salmonella enterica現場快篩再快一點，食安很需要。
Microbial Biofilm Formation to Mitigate Foodborne Pathogens Strategies and Control Measures¶
Authors: Alsuwat MA et al. | Journal: Indian J Microbiol | Date: 2026 Jun
DOI: 10.1007/s12088-025-01461-4
TL;DR: 食媒病原biofilm綜論整理Salmonella、E. coli、L. monocytogenes的quorum sensing、adhesion與EPS機制，並比較化學、物理、phage與enzyme控制策略。
不嘻嘻：biofilm老問題大全，清不乾淨才是日常。
資料來源：PubMed (articles retrieved 2026-06-23)