Daily Journal Digest — 2026-06-11¶
過去 24 小時新增：Transplant ID × 11、One Health × 10、Food Security × 11，共 32 篇。
🔴 Transplant & Opportunistic Infections¶
Risk factors for EBV reactivation and impact of graft composition following GVHD prophylaxis with rabbit ATG or PTCy¶
Authors: Thiant S et al. | Journal: Bone Marrow Transplant | Date: 2026 Jun 09
DOI: 10.1038/s41409-026-02902-4
TL;DR: Allogeneic HCT 286人中，ATG較PTCy更早且更常出現高EBV DNAemia（42.3% vs 22.5%）；PTLD全發生於ATG組，且高CD19+ graft負荷提高風險。
不嘻嘻：ATG救命，也順手把EBV請進派對。
Tuberculosis After Allogeneic Hematopoietic Cell Transplant: A 15-Year Case Series Highlighting Diagnostic Challenges¶
Authors: Figueroa-Ortiz C et al. | Journal: Transplant Cell Ther | Date: 2026 Jun 09
DOI: 10.1016/j.jtct.2026.06.007
TL;DR: 15年10例allogeneic HCT後TB，中位122天發病，4例disseminated TB、3例死亡；7例篩檢僅3例陽性，凸顯現行latent TB篩檢限制。
不嘻嘻：HCT後TB像躲貓貓，找到時常已很難笑。
Changes in unrelated donor usage for allogeneic hematopoietic cell transplant in Canada: 2013-2023 and identifying priorities in donor selection¶
Authors: Hasan T et al. | Journal: Transfusion | Date: 2026 Jun 10
DOI: 10.1111/trf.70285
TL;DR: 加拿大2023年500例unrelated donor HCT中，83%用HLA-matched donor，本國donor僅10%；年輕、男性、CMV matching與ABO資料可得性主導選擇。
嘻嘻：donor選擇越精準，移植團隊少掉幾根白髮。
Lumbar Spine Mucormycosis Mimicking Pott's Spine: A Case Report¶
Authors: Gupta K et al. | Journal: Case Rep Infect Dis | Date: 2026
DOI: 10.1155/crdi/1299422
TL;DR: 54歲Child-Pugh C cirrhosis患者lumbar mucormycosis誤似Pott’s spine，術後12天死於multiorgan failure；免疫低下且神經惡化時需早期取組織診斷。
不嘻嘻：黴菌偽裝成TB，臨床醫師真的沒在輕鬆。
From targets to real world impact: a review of models of care for chronic HBV and HCV in Europe¶
Authors: Picchio CA et al. | Journal: Lancet Reg Health Eur | Date: 2026 Jun
DOI: 10.1016/j.lanepe.2026.101712
TL;DR: 歐洲約2900萬人有慢性HBV/HCV，viral hepatitis死亡已超過HIV/AIDS與TB總和；2015–2025年MoC顯示去中心化、point-of-care與監所介入有助消除目標。
嘻嘻：把照護送到現場，hepatitis消除才有戲。
Rhino-Orbital-Cerebral Mucormycosis With Bilateral Endogenous Aspergillus Endophthalmitis Following Steroid Therapy for COVID-19 Infection¶
Authors: Shoeibi N et al. | Journal: Case Rep Ophthalmol Med | Date: 2026
DOI: 10.1155/crop/6610355
TL;DR: 糖尿病患者COVID-19後接受高劑量steroid，併發ROCM與雙眼endogenous Aspergillus endophthalmitis；amphotericin B與posaconazole後右眼病灶改善。
不嘻嘻：steroid用完換黴菌登場，劇本太狠了。
Abnormal Liver Function at the Time of Tuberculosis Diagnosis in South India¶
Authors: Sharma K et al. | Journal: Indian J Community Med | Date: 2026 Apr
DOI: 10.4103/ijcm.ijcm_579_24
TL;DR: 印度Puducherry 1809名drug-sensitive TB患者診斷時7.5%已有ALF；HIV陽性14%、重度貧血16%、危險飲酒11%，支持高風險者ATT前驗肝功能。
不嘻嘻：TB藥還沒上，肝臟先舉白旗。
Describing the burden and characteristics of Aspergillus-related chronic lung disease at Imperial College Healthcare Trust: a 10-year retrospective study¶
Authors: Venkatesan T et al. | Journal: BMJ Open Respir Res | Date: 2026 Jun 09
DOI: 10.1136/bmjresp-2025-003997
TL;DR: 倫敦10年資料納入334例sABPA、145例ABPA、74例CPA與38例aspergilloma；ABPA有較高A. fumigatus-IgE與IgG/precipitins陽性率。
不嘻嘻：Aspergillus慢性肺病，存在感比想像中強。
Recommendations on the Diagnosis and Treatment of Tuberculosis Infection: SEPAR/SEIMC/Spanish Ministry of Health Consensus Statement¶
Authors: Caminero JA et al. | Journal: Enferm Infecc Microbiol Clin (Engl Ed) | Date: 2026
DOI: 10.1016/j.eimce.2025.503037
TL;DR: 西班牙TBI共識建議高風險族群篩檢，IGRA優先於TST；排除active TB後給TPT，首選3HR，rifapentine可用後可採1HP或3HP。
嘻嘻：TBI策略整理清楚，門診終於少一點猜謎。
Screening for Imported Infections in Pediatric Patients Prior to Immunosuppressive Therapy¶
Authors: Del Rosal T et al. | Journal: Travel Med Infect Dis | Date: 2026 Jun 08
DOI: 10.1016/j.tmaid.2026.102999
TL;DR: 馬德里63名免疫抑制前兒童移民篩檢，僅19%完成全套；28.6%檢出至少一種imported infection，toxoplasmosis 12.3%、strongyloidiasis 8.9%。
不嘻嘻：篩檢沒做完，寄生蟲先替病歷補空格。
Inclusion of young adolescents in policy development for new tuberculosis vaccines¶
Authors: Hatherill M et al. | Journal: Lancet Glob Health | Date: 2026 Jun 08
DOI: 10.1016/S2214-109X(26)00017-3
TL;DR: 年輕青少年（9–14歲）納入新TB vaccine政策可趕在TB風險上升前接種，但低發病率與低M. tuberculosis sensitisation使efficacy trial更困難。
嘻嘻：TB vaccine往青春期前推，方向很有前瞻性。
🟢 One Health / Zoonoses¶
Reverse Genetics of Orthoflaviviruses: Strategies for Constructing Functional or Infectious cDNA¶
Authors: Lee YM | Journal: J Med Virol | Date: 2026 Jun
DOI: 10.1002/jmv.71007
TL;DR: Orthoflavivirus reverse genetics從RNA-launched走向DNA-launched，但全長cDNA在細菌中不穩定；Gibson assembly等bacteria-free策略可改善建構瓶頸。
嘻嘻：reverse genetics少靠細菌，病毒工具箱升級了。
Prevalence of cryptosporidiosis and other enteric pathogens in calves in France: effects of rotavirus, coronavirus and E. coli vaccination and transmission routes¶
Authors: Costa D et al. | Journal: Vet Res | Date: 2026 Jun 09
DOI: 10.1186/s13567-025-01609-6
TL;DR: 法國1159份牛犢與母牛糞便中，Cryptosporidium最常見；母牛產前疫苗後僅16%牛犢有症狀，genotype支持以calf-to-calf與環境傳播為主。
嘻嘻：牛犢疫苗策略有用，牧場腹瀉少點災情。
Pathogenic characterization and genome-wide evolutionary analysis of Bacillus anthracis from a cutaneous anthrax case in Inner Mongolia, China¶
Authors: Hu J et al. | Journal: BMC Microbiol | Date: 2026 Jun 09
DOI: 10.1186/s12866-026-05156-8
TL;DR: 中國內蒙古2023年cutaneous anthrax事件中，18件樣本4件PCR陽性，病人、羊肉、羊皮與車輛分離株皆為B. anthracis A.Br.001/002 lineage。
不嘻嘻：anthrax還會循線回來，羊肉也能辦案。
Invasion dynamics of antimicrobial-resistant E. coli in river biofilms: impacts on the resistome, microbiomes, and horizontal gene transfer¶
Authors: Gionchetta G et al. | Journal: NPJ Antimicrob Resist | Date: 2026 Jun 09
DOI: 10.1038/s44259-026-00232-5
TL;DR: 河川biofilm暴露帶IncPα plasmid的AMR E. coli後，48小時達峰、14天近背景值；wastewater影響區plasmid下降較慢，HGT整體有限。
不嘻嘻：AMR進biofilm巡迴演出，幸好沒長住。
A global analysis of the inclusion of wildlife in national action plans for antimicrobial resistance¶
Authors: Bor N et al. | Journal: JAC Antimicrob Resist | Date: 2026 Jun
DOI: 10.1093/jacamr/dlag100
TL;DR: 177份AMR national action plans僅11%提及野生動物，58次引用多停留在One Health概念或監測建議；只有烏干達納入野生動物機構治理架構。
不嘻嘻：One Health喊很大，野生動物還在門外。
Carbapenemases: epidemiology, detection and management in a changing global landscape¶
Authors: Macesic N et al. | Journal: JAC Antimicrob Resist | Date: 2026 Jun
DOI: 10.1093/jacamr/dlag099
TL;DR: Carbapenemase-producing Gram-negative bacteria已擴及Enterobacterales、P. aeruginosa與A. baumannii；治療需依KPC、OXA或MBL機轉選擇新BL/BLI、aztreonam組合或cefiderocol。
不嘻嘻：carbapenemase變化太快，抗生素表快背到哭。
Extrahepatic hepatitis E virus in cerebrospinal fluid of people living with human immunodeficiency virus at an Academic Hospital, South Africa¶
Authors: Modise LM et al. | Journal: Int J Infect Dis | Date: 2026 Jun 08
DOI: 10.1016/j.ijid.2026.108834
TL;DR: 南非54份PLWHIV CSF中，HEV RNA PCR陽性率61%（33/54），11條序列近似HEV genotype 3；為當地首度報告CSF extrahepatic HEV。
不嘻嘻：HEV跑到CSF，病毒真的很會找新舞台。
Coxiella burnetii in the Arabian Peninsula: A One Health Perspective Through Systematic Review and Meta-Analysis¶
Authors: Aldwekat AFM et al. | Journal: Transbound Emerg Dis | Date: 2026
DOI: 10.1155/tbed/8897201
TL;DR: 阿拉伯半島64篇研究meta-analysis估計C. burnetii人類seroprevalence 20.3%、反芻動物40.7%；tick infestation反芻動物高達74.0%。
不嘻嘻：C. burnetii橫跨人畜蜱，One Health考題又來。
Clinical, socioeconomic and surgical characteristics of surgically treated cystic echinococcosis patients in Jordan¶
Authors: Hizzani Y et al. | Journal: Parasitol Int | Date: 2026 Jun 09
DOI: 10.1016/j.parint.2026.103320
TL;DR: 約旦安曼83例手術確認cystic echinococcosis，61.5%肝臟、21.7%肺部；女性占78.3%，18–30歲最多，肝臟手術住院期較肺部短。
不嘻嘻：cystic echinococcosis仍在開刀房刷存在感。
Vitamin D3 contribution to systemic and local control of Salmonella Typhimurium infection in an in vivo mouse model¶
Authors: Tarantino M et al. | Journal: Front Mol Biosci | Date: 2026
DOI: 10.3389/fmolb.2026.1816390
TL;DR: 小鼠S. Typhimurium colitis模型中，1,25(OH)2D3在感染後3天降低bacterial burden、組織發炎與免疫失衡，並延長存活，支持作為免疫調節輔助策略。
嘻嘻：vitamin D3幫免疫踩煞車，老分子有新戲。
🟡 Food Security / Food Safety¶
Historical and projected trends of long-term nitrogen dynamics from China's mariculture¶
Authors: Liu J et al. | Journal: Nat Commun | Date: 2026 Jun 09
DOI: 10.1038/s41467-026-73843-1
TL;DR: 中國mariculture氮排放1983–2024年增150倍至93.73–128.37 kilotons；目前淨移除-9.36 kilotons，但多數情境2030年前恐轉為淨來源。
不嘻嘻：養殖氮帳本快翻紅，海也會記帳。
Engineering an amino-modified MOF@COF interface to construct a light-responsive oxidase-like nanozyme for rapid total antioxidant capacity assay in foods¶
Authors: Feng Y et al. | Journal: Food Chem | Date: 2026 Jun 02
DOI: 10.1016/j.foodchem.2026.149908
TL;DR: UiO-66-NH2@TpPa-COF在365 nm光下具oxidase-like活性，用於食品TAC colorimetric assay，AA線性0.02–60 μM、LOD 5.988 nM，回收率96–107%。
嘻嘻：食品抗氧化檢測變快，實驗室會想點頭。
Synergistic Dual-Nano Delivery Systems for Enhanced Foliar Deposition and Disease Control¶
Authors: Xu X et al. | Journal: J Agric Food Chem | Date: 2026 Jun 10
DOI: 10.1021/acs.jafc.6c00810
TL;DR: DIF-PYR nanoemulsion與PLGA nanosuspension提升葉面沉積與控釋，較傳統formulations更能控制Botrytis cinerea、Fusarium oxysporum與F. graminearum。
嘻嘻：nano delivery黏得住葉面，農藥終於少點漂泊。
Socioeconomic determinants of practical adaptive capacity and food security under climate stress in Western Iran¶
Authors: Pakravan-Charvadeh MR | Journal: Sci Rep | Date: 2026 Jun 09
DOI: 10.1038/s41598-026-57040-0
TL;DR: 伊朗西部296戶小農survey顯示，multidimensional adaptive capacity越高，household food insecurity越低；教育、資產與資訊可近性與適應強度正相關。
不嘻嘻：氣候壓力下，窮不是風險因子是主線。
Enhancing the detection of LTP through lyophilized protein samples and NIR spectroscopy with explainable deep learning¶
Authors: Osa-Sanchez A et al. | Journal: Sci Rep | Date: 2026 Jun 10
DOI: 10.1038/s41598-026-56935-2
TL;DR: 整合NIRS與deep learning分析11688筆光譜，加入purified LTP embeddings後CNN辨識LTP達95.8% accuracy、AUC-ROC 0.954，可用於食品allergen detection。
嘻嘻：NIRS抓allergen更準，食品安全多一雙眼。
Identification of targetable epitope surfaces from the high resolution structure of the superantigen Staphylococcal enterotoxin L¶
Authors: Klamm E et al. | Journal: Sci Rep | Date: 2026 Jun 09
DOI: 10.1038/s41598-026-54870-w
TL;DR: Staphylococcal enterotoxin L crystal structure首次解析，並以T cell activation assays確認superantigen功能；比對SEI/SEK/SEM/SEQ後定位SEL特異epitope。
嘻嘻：superantigen結構解出來，抗體設計更有方向。
Biopolymer-Based Food Packaging: Functional Properties, Enhancement Strategies, and Future Perspectives¶
Authors: Bayrak S et al. | Journal: Food Sci Nutr | Date: 2026 Jun
DOI: 10.1002/fsn3.72005
TL;DR: Biopolymer food packaging具biodegradability與較低碳足跡，但受高濕敏感、機械強度差與scale-up限制；nanocomposite可讓barrier performance提升30–50%。
嘻嘻：包材想環保又實用，材料科學還有得拚。
Enhancing Surveillance of Foodborne Bacteria and Antimicrobial Resistance Using a Large Centralized Laboratory Database: Case Study of Campylobacter and Non-Typhoidal Salmonella in Peru¶
Authors: Gómez de la Torre JC et al. | Journal: Int J Infect Dis | Date: 2026 Jun 09
DOI: 10.1016/j.ijid.2026.108868
TL;DR: 秘魯47724份stool culture中，Campylobacter陽性4.1%、NTS 2.2%；C. jejuni與C. coli ciprofloxacin resistance皆>95%，NTS ceftriaxone resistance 40.6%。
不嘻嘻：ciprofloxacin resistance爆表，腸胃炎也不單純。
A Retrieval-Augmented Natural Language Interface for Data Description and Meta-Analysis in the Pathogens-in-Foods (PIF) Database¶
Authors: Silva LR et al. | Journal: J Food Prot | Date: 2026 Jun 09
DOI: 10.1016/j.jfp.2026.100829
TL;DR: PIF database的retrieval-augmented natural-language interface在10題benchmark中tool selection與retrieval皆100%；Toxoplasma case study數值一致性100%。
嘻嘻：RAG接上食品病原資料庫，查資料像開外掛。
Relationship Between Food Insecurity and Mental Distress in Firefighters¶
Authors: Hashemi S et al. | Journal: J Nutr Educ Behav | Date: 2026 Jun 09
DOI: 10.1016/j.jneb.2026.04.015
TL;DR: 美國88名現役消防員中22.7%有food insecurity，27.2%達臨床焦慮、43.2% PTSD陽性；food insecurity與焦慮rs=0.27、飲食品質rs=-0.31相關。
不嘻嘻：消防員連吃飯都不穩，心理壓力更難收拾。
Packaged Curd and Food Poisoning in Kutch: An Outbreak Across Logistically Challenged Stations¶
Authors: Vardhan P et al. | Journal: Indian J Community Med | Date: 2026 Apr
DOI: 10.4103/ijcm.ijcm_79_25
TL;DR: 印度古吉拉特Kutch兩地280人食用同源packaged curd後腸胃炎，curd attack rate 33.4%、潛伏期18–23.5小時；stool確認S. Chester。
不嘻嘻：一杯curd放倒一群人，食安真的不能賭。
資料來源：PubMed (articles retrieved 2026-06-11)