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Daily Journal Digest — 2026-06-01

過去 24 小時新增:Transplant ID × 3、One Health × 10、Food Security × 11,共 24 篇。

🔴 Transplant & Opportunistic Infections

Clinical and analytical evaluation of a commercial Aspergillus fumigatus real-time PCR assay for the diagnosis of invasive pulmonary aspergillosis in patients with hematological malignancies

Authors: Gibert C et al. | Journal: J Infect Dis | Date: 2026 May 31
DOI: 10.1093/infdis/jiag280
TL;DR: 153 名 hematological malignancies 成人中,A. fumigatus qPCR 以 1 次陽性診斷 IPA sensitivity 0.73、specificity 0.71;2 次陽性降至 0.31、升至 0.93,且有 cross-reactivity。

不嘻嘻:PCR 也會眼花,IPA 診斷還是要多帶一點懷疑人生。


Candidemia in Turkey demonstrates nationwide predominance of non-albicans Candida and Candida auris detection

Authors: Karakoç ZÇ et al. | Journal: Sci Rep | Date: 2026 May 30
DOI: 10.1038/s41598-026-53506-3
TL;DR: 土耳其 20 院 398 例 candidemia 中,NAC 占 65.3%,C. auris 6.5%;30 天死亡率 56.3%,未移除 CVC 與較高死亡率獨立相關。

不嘻嘻Candida 換班上陣,CVC 還不拔就是幫它加班。


Analysis of the efficacy and survival of allogeneic hematopoietic stem cell transplantation and nontransplantation treatment in chronic active Epstein-Barr virus infection

Authors: Ming X et al. | Journal: Cell Transplant | Date: 2026
DOI: 10.1177/09636897261443609
TL;DR: 75 名 CAEBV 回溯分析顯示,allogeneic HSCT 較 non-HSCT 改善 ORR、3 年 OS 與 EFS;HLH 是較差 survival 的獨立風險因子。

嘻嘻:CAEBV 終於有比較像出口的路,雖然路況仍很硬。


🟢 One Health / Zoonoses

Molecular detection of zoonotic pathogens in fleas collected from dogs and cats in Portugal

Authors: Pereira A et al. | Journal: Parasit Vectors | Date: 2026 May 30
DOI: 10.1186/s13071-026-07456-4
TL;DR: 葡萄牙犬貓 1261 隻 flea 中,24.7% 帶至少一種 pathogen;Bartonella spp. 8.3%、Rickettsia spp. 16.2%、D. caninum 1.8%,支持 One Health 監測。

不嘻嘻:跳蚤小歸小,帶的麻煩倒是一點都不客氣。


Deforestation's Impact On BrazilianCulexMosquitoes And Arboviral Spillover risk

Authors: Hughes A et al. | Journal: Acta Trop | Date: 2026 May 29
DOI: 10.1016/j.actatropica.2026.108161
TL;DR: 巴西亞馬遜 deforestation、畜牧擴張與非管制都市化可能改變 Culex ecology 與 arboviral spillover 風險;現有監測明顯偏向 AedesAnopheles

不嘻嘻:森林一退,vector 生態就開始幫人類寫恐怖劇本。


Short Report: Update on CCHFV Seroprevalence in Mauritanian Camels and Cattle Sampled Between 2020 and 2021

Authors: Beyit AD et al. | Journal: Trop Med Int Health | Date: 2026 May 29
DOI: 10.1111/tmi.70175
TL;DR: 茅利塔尼亞 317 份牛與駱駝血清中,CCHFV seroprevalence 達 70%;駱駝 >81%、牛 >60%,年齡增加與 seropositivity 顯著相關。

不嘻嘻:CCHFV 在牲畜圈這麼熱鬧,人類只能安靜冒汗。


Trained immunity agonists given to neonatal mice fail to protect against leptospiral infection in adulthood and may cause adverse effects

Authors: Fernandez M et al. | Journal: Innate Immun | Date: 2026
DOI: 10.1177/17534259261455983
TL;DR: Neonatal mice 於 7/14 或 14/21 日齡給 CL429、MDP 或 β-glucan,成年後未誘發 protective TI 或防 leptospirosis;MDP 組感染後死亡率達 50%。

不嘻嘻:trained immunity 沒練成,副作用倒是先畢業了。


Mapping antimicrobial resistance interventions in ASEAN countries: a scoping review of implementation patterns, One Health integration, and evidence gaps

Authors: Nazari R et al. | Journal: Trop Med Health | Date: 2026 May 30
DOI: 10.1186/s41182-026-00992-w
TL;DR: ASEAN AMR intervention scoping review 篩選 9832 筆、納入 57 篇;70.2% 來自泰國、新加坡、越南,86.0% 聚焦 human health,僅 8.8% 採 One Health。

不嘻嘻:AMR 說要 One Health,結果大家還在各唱各的。


Comparative analysis of Pharmaceutical Care practice in rural and urban community pharmacies in Valencia, Spain: a quasi-experimental study

Authors: Gutiérrez-Igual S et al. | Journal: BMC Health Serv Res | Date: 2026 May 30
DOI: 10.1186/s12913-026-14739-0
TL;DR: 西班牙瓦倫西亞社區藥局 quasi-experimental study 顯示,pharmacist-led intervention 在 urban 與 rural 皆顯著降低 DRPs;介入接受度與地區、DRP 類別及建議型態相關。

嘻嘻:pharmacist 出手有用,城鄉藥局都能少踩 DRP 地雷。


Advances in rapid microbiological testing for animal diseases: A review

Authors: Zhen Z et al. | Journal: J Microbiol Methods | Date: 2026 May 29
DOI: 10.1016/j.mimet.2026.107564
TL;DR: 動物疾病 rapid microbiological testing review 指出,LAMP/RPA 合併 CRISPR-Cas 最適合 POC veterinary diagnostics;qPCR/dPCR 仍適用定量監管與疫苗效力監測。

嘻嘻:獸醫 POC 工具越來越快,現場診斷終於不只靠等。


Molecular epidemiology and genetic profiling of Anaplasma ovis, Bartonella sp., and Toxoplasma gondii in domestic cats

Authors: Rehman FT et al. | Journal: Comp Immunol Microbiol Infect Dis | Date: 2026 May 27
DOI: 10.1016/j.cimid.2026.102488
TL;DR: 巴基斯坦 144 隻家貓 PCR 顯示,A. ovisT. gondiiBartonella sp. 感染率分別為 15%、7%、4%;亦偵測雙重 co-infection。

不嘻嘻:貓咪看似淡定,身上 pathogen 名單可不短。


Inhibiting horizontal gene transfer to contain antimicrobial resistance: conjugation and plasmid maintenance as druggable targets

Authors: Touati A et al. | Journal: Expert Rev Anti Infect Ther | Date: 2026 May 30
DOI: 10.1080/14787210.2026.2683605
TL;DR: AMR containment review 指出,抑制 HGT 可補強 stewardship 與 infection control;conjugation、type IV secretion、plasmid replication/partition 與 toxin-antitoxin 是可 druggable targets。

嘻嘻:直接卡住 plasmid 社交,AMR 戰場多了一招。


Bioinformatics-based B-cell epitope identification from Leptospira interrogans outer membrane proteins LIC11574 and LIC13411 for the rational development of a multi-epitope anti-Leptospira vaccine

Authors: Porcalla JM et al. | Journal: Arch Microbiol | Date: 2026 May 30
DOI: 10.1007/s00203-026-04922-6
TL;DR: Leptospira interrogans LIC11574 與 LIC13411 分別篩得 69/68 與 112/123 個 16-mer/18-mer B-cell epitopes;top epitopes 與 HLA-DRB1*15 docking affinity 為 -12.6 至 -14.9 kcal/mol。

嘻嘻:vaccine 設計先用 in silico 篩牌,至少起手式漂亮。


🟡 Food Security / Food Safety

Dry Cleaning and Post-Cleaning Strategies in Food Processing Facilities: A Scoping Review

Authors: Shahbazi Z et al. | Journal: Compr Rev Food Sci Food Saf | Date: 2026 Jul
DOI: 10.1111/1541-4337.70525
TL;DR: 2014–2024 scoping review 納入 91 篇 dry-food facility 清潔研究;cold atmospheric plasma 與 dry steam 在最佳條件下常達 5–7 log CFU microbial reduction。

嘻嘻:乾式清潔也能有狠招,食品廠終於多些選項。


Progress in the application of high internal phase emulsions in weight-loss food development: Mechanisms, effects, applications and integration with artificial intelligence

Authors: Du X et al. | Journal: Food Chem | Date: 2026 May 05
DOI: 10.1016/j.foodchem.2026.149533
TL;DR: HIPEs 可藉 gut microbiota modulation、取代 saturated/trans fats、延緩 lipid digestion,改善 weight-loss food 口感、飽足感與熱量控制;AI 可支援個人化設計。

嘻嘻:減重食品若能好吃又聰明,意志力也能少加班。


Design of magnetic coral-like mesoporous carbon materials for highly effective solid-phase extraction of bisphenols in food samples

Authors: Li D et al. | Journal: Food Chem | Date: 2026 May 28
DOI: 10.1016/j.foodchem.2026.149854
TL;DR: MPC-600 用於 food bisphenols magnetic solid-phase extraction,2 分鐘達吸附平衡,容量 286.9–693.1 mg/g;LOD 0.02–0.03 ng/mL,回收率 81.2%–114.9%。

嘻嘻:食品檢測抓 bisphenols 越快,消費者越能少猜。


Empowering fungal infection research with single-cell RNA sequencing

Authors: Toth R et al. | Journal: Commun Biol | Date: 2026 May 29
DOI: 10.1038/s42003-026-10304-x
TL;DR: Fungal infection scRNA-seq review 強調,此技術可解析 host-fungal pathogen interaction 的 cellular heterogeneity、biomarker 與 intervention targets,但 fungal 領域應用仍落後。

嘻嘻:fungal scRNA-seq 補上來,host-pathogen 細節終於開燈。


Recent advances in spore-killing technologies: A comprehensive review on killing effect, mechanism and application in food matrices

Authors: Li C et al. | Journal: Food Microbiol | Date: 2026 Oct
DOI: 10.1016/j.fm.2026.105157
TL;DR: Bacterial spore non-thermal inactivation review 比較多種食品矩陣技術,指出可兼顧 spore control 與 food quality,但仍需釐清機制、標準化驗證與實廠應用限制。

嘻嘻:spore control 有新工具箱,食品安全不必只靠高溫硬拚。


Phenotypic and genomic analysis of Arcobacter cryaerophilus in response to different stress conditions

Authors: Bachus A et al. | Journal: Food Microbiol | Date: 2026 Oct
DOI: 10.1016/j.fm.2026.105149
TL;DR: 11 株 Arcobacter cryaerophilus 皆可在 aerobic 與 10°C 生長,對 4 mM citric acid、2.5% NaCl 呈 strain-dependent susceptibility,42°C 則全株易受抑制。

不嘻嘻Arcobacter 適應力這麼好,冰箱也沒那麼像安全區。


Incidence of foodborne viruses in Crassostrea virginica oysters cultured in the Magdalen Islands region of Eastern Canada

Authors: Manseau-Ferland K et al. | Journal: Food Microbiol | Date: 2026 Oct
DOI: 10.1016/j.fm.2026.105150
TL;DR: 加拿大東部馬德蓮群島 52 份 Crassostrea virginica oyster 樣本中,HuNoV GI RNA 6 份、GII RNA 1 份陽性;HAV、HEV RNA 皆未偵測。

不嘻嘻:生蠔又提醒我們,浪漫海味常附贈病毒焦慮。


Genomic and transcriptomic analysis of biofilm formation in foodborne Listeria monocytogenes isolates under combined environmental stress

Authors: Liu Z et al. | Journal: Food Microbiol | Date: 2026 Oct
DOI: 10.1016/j.fm.2026.105148
TL;DR: 中國 70 株 foodborne Listeria monocytogenes 中,85.7% 屬 lineage II、以 CC8 為主;pH 6 促進 biofilm,pH 5 或 5% NaCl 則降低形成。

不嘻嘻Listeria biofilm 看環境長臉色,清潔班真的辛苦。


Survival and genomic adaptation of Listeria monocytogenes in long-term culture

Authors: Benetti S et al. | Journal: Food Microbiol | Date: 2026 Oct
DOI: 10.1016/j.fm.2026.105147
TL;DR: Listeria monocytogenes long-term culture 顯示,4°C 可維持 culturability 且 mutation/VBNC 較少;30°C 部分培養於 180–365 天失去培養能力並累積更多 mutation。

不嘻嘻Listeria 在低溫慢慢撐,食品保存又被上一課。


Inactivation mechanisms of cold plasma on Bacillus cereus biofilms and its application in simulated meat processing environments

Authors: Wu X et al. | Journal: Food Microbiol | Date: 2026 Oct
DOI: 10.1016/j.fm.2026.105134
TL;DR: APPJ 處理 240 秒可使玻璃表面 Bacillus cereus biofilm 降低 3.77 log CFU;模擬牛肉屠宰與加工 biofilm 則降 5.92、6.35 log CFU。

嘻嘻:cold plasma 打 biofilm 有感,肉品環境清潔多一把刀。


Development, functional profiling, and probiotic evaluation of indigenous LAB from Nigerian fermented foods: Antimicrobial mechanisms, in vivo validation, and applications in food preservation and mycotoxin risk reduction

Authors: Mafe AN et al. | Journal: World J Microbiol Biotechnol | Date: 2026 May 30
DOI: 10.1007/s11274-026-05051-4
TL;DR: 奈及利亞發酵食品 isolates 中,L. fermentumW. confusa 具 in vivo host protection;L. fermentum 可延長 zobo beverage 保存 17–21 天,並抑制多種 foodborne pathogens。

嘻嘻:local LAB 不只好吃,還能順手守住食品安全。


資料來源:PubMed (articles retrieved 2026-06-01)