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Daily Journal Digest — 2026-05-30

過去 24 小時新增:Transplant ID × 22、One Health × 10、Food Security × 11,共 43 篇。

⭐ 今日亮點


🔴 Transplant & Opportunistic Infections

Transcriptomic and lipidomic analysis of the cryptococcal lung granuloma reveals macrophage boundary programs and sphingolipid remodeling

Authors: Brauer VS et al. | Journal: Nat Commun | Date: 2026-05-28
DOI: 10.1038/s41467-026-73516-z
TL;DR: 以轉錄體學與脂質體學解析小鼠cryptococcosis肺部肉芽腫:巨噬細胞邊界亞型差異表現與sphingolipid重塑在宿主防禦中扮演關鍵角色,為免疫調節治療提供新靶點。

嘻嘻!Nature Commun解密肉芽腫的sphingolipid語言,未來或許能以免疫調節輔助cryptococcosis治療。


Risk prediction of pneumocystis jirovecii pneumonia in kidney transplant recipients using a clinical nomogram

Authors: Liu Q et al. | Journal: Front Cell Infect Microbiol | Date: 2026-05-13
DOI: 10.3389/fcimb.2026.1778937
TL;DR: 腎臟移植受者PJP風險預測nomogram(CD4+ T cell count、CD8/淋巴球比值、血糖、嗜中性球百分比、CRP)在驗證組AUC達0.89,可識別需延長預防性投藥的高風險族群。

嘻嘻!自動化nomogram幫忙找出需要延長PJP預防的病人,實用工具登場。


Burden and Challenges in the Diagnosis and Treatment of Histoplasmosis Among Persons With Advanced HIV Disease in Uganda, 2025

Authors: Kasone V et al. | Journal: Open Forum Infect Dis | Date: 2026-05-14
DOI: 10.1093/ofid/ofag302
TL;DR: 烏干達332名HIV晚期患者中histoplasmosis盛行率2.4%,因抗真菌藥物取得困難無一人接受建議治療,存活率尚可,藥物可近性為最主要挑戰。

不嘻嘻:—沒藥、沒錢、沒指引知識,烏干達histoplasmosis病患只能靠自身免疫力撐著。


Development of VP1 based indirect ELISAs for BK and JC polyomaviruses with seroprevalence assessment and cross reactivity evaluation

Authors: Alipour AH et al. | Journal: Sci Rep | Date: 2026-05-28
DOI: 10.1038/s41598-026-38907-8
TL;DR: 開發baculovirus表現VP1蛋白的間接ELISA:BK virus血清盛行率77.6%、JCV 34.3%,兩者無交叉反應,可供移植後polyomavirus風險族群的血清流行病學監測。

嘻嘻!BKV/JCV血清工具升級,移植後多瘤病毒監測有了更精準的利器。


Prevalence and Risk Factors for Cytomegalovirus Retinitis Among People Living with HIV in Sub-Saharan Africa in the Antiretroviral Therapy Era: A Systematic Review and Meta-Analysis

Authors: Ismail MF et al. | Journal: Sci Rep | Date: 2026-05-28
DOI: 10.1038/s41598-026-48848-x
TL;DR: 非洲撒哈拉以南HIV患者CMV retinitis統合分析(1,931人):pooled盛行率3%,CD4 <50 cells/μL為最強危險因子,東非(7%)遠高於西非(<1%),系統性視網膜篩檢仍不足。

不嘻嘻:—CD4低的HIV患者CMV retinitis仍被嚴重低估,非洲預防失明需要更多資源投入。


Clinical characteristics, diagnosis, and management of central nervous system aspergillosis in children: a single-center experience

Authors: Feng W et al. | Journal: BMC Infect Dis | Date: 2026-05-28
DOI: 10.1186/s12879-026-13675-y
TL;DR: 小兒CNS aspergillosis 16例:56%初診誤判,CSF mNGS敏感度優於培養,含liposomal amphotericin B方案反應率顯著優於voriconazole單藥(75–80% vs. 22%),全因死亡率37.5%。

不嘻嘻:—超過一半誤診,死亡率高,voriconazole單藥根本不夠用,L-AmB是關鍵。


Congenital cytomegalovirus and associations with maternal HIV serostatus and child health outcomes in Uganda

Authors: Adong J et al. | Journal: BMC Infect Dis | Date: 2026-05-28
DOI: 10.1186/s12879-026-13655-2
TL;DR: 烏干達793名新生兒唾液CMV篩檢:先天性CMV盛行率3.4%,與母親HIV血清狀態無顯著差異,CMV陽性與聽力損失無直接相關,但與低Apgar分數及黃疸有關。

母親HIV不增加先天CMV感染風險,略嘻嘻;但非洲新生兒CMV篩檢仍極不普及,令人憂心。


Diagnostic Accuracy of Metagenomic Next-Generation Sequencing for Invasive Pulmonary Aspergillosis: A Systematic Review and Meta-Analysis

Authors: Lv H et al. | Journal: Int J Infect Dis | Date: 2026-05-27
DOI: 10.1016/j.ijid.2026.108827
TL;DR: 12項研究統合:mNGS診斷侵襲性肺部aspergillosis敏感度0.75、特異度0.93,較galactomannan(+22%)和培養(+40%)具更高敏感度,BALF為最佳檢體。

mNGS敏感度贏傳統方法,嘻嘻!但75%仍有遺漏,與galactomannan合併使用或許更佳。


The Effect of High-Velocity Elastic Band Training on Physical Performance in Youth Soccer Players

Authors: Bartusevičius D et al. | Journal: J Strength Cond Res | Date: 2026-05-29
DOI: 10.1519/JSC.0000000000005515
TL;DR: 【非相關文獻】青少年足球訓練研究因縮寫「BKV」(ball-kicking velocity)觸發PubMed搜尋字串意外納入,內容與感染症無關。

今天的BKV是踢球速度,不是BK virus:—PubMed縮寫碰撞趣事,跟感染科無關。


Epidemiology, Distribution, Key Characteristics, and Challenges of Candidozyma auris (Formerly Candida auris): A Narrative Review With a Special Focus on Türkiye

Authors: Gökmen R et al. | Journal: Cureus | Date: 2026-04-27
DOI: 10.7759/cureus.107778
TL;DR: 回顧Candidozyma auris(原Candida auris)全球流行病學:多重抗藥性、生物膜形成、實驗室鑑定困難;土耳其以Clade I為主,需加強感控及監測系統。

不嘻嘻:—C. auris改名沒有讓它更好對付,多重抗藥的醫院感染威脅依然存在。


invasion of the orbital compartment and periocular spaces following intracerebral infection in mice

Authors: Munzen ME et al. | Journal: iScience | Date: 2026-05-20
DOI: 10.1016/j.isci.2026.115973
TL;DR: 小鼠intracerebral Cryptococcus neoformans H99感染模型:病原可由腦部基底核侵入眼眶及眼周組織,莢膜多醣在眼部結構中蓄積,提示腦膜炎後視力損害及復發的新機制。

不嘻嘻:—Cryptococcus跑進眼眶,腦膜炎後視力問題又多了一個令人憂心的解釋。


Concurrent pretreatment serum and BALF galactomannan positivity as a prognostic indicator in non-neutropenic invasive pulmonary aspergillosis without malignancy or solid organ transplantation: a retrospective cohort study

Authors: Tang D et al. | Journal: Front Med (Lausanne) | Date: 2026-05-13
DOI: 10.3389/fmed.2026.1809671
TL;DR: 非嗜中性球低下IPA患者中,血清與BALF galactomannan雙陽性者30天死亡率達45.7%(vs. 13.6%),是30天全因死亡的獨立預測因子(adjusted HR 3.07)。

雙GM雙陽=三倍死亡風險,早期風險分層又多一個工具,嘻嘻但也令人不安。


Treating allergic bronchopulmonary aspergillosis with hormone therapy: natural disease course, regimens, compliance, and outcomes

Authors: Wu Q et al. | Journal: Front Med (Lausanne) | Date: 2026-05-13
DOI: 10.3389/fmed.2026.1760447
TL;DR: ABPA患者類固醇治療4週後依從性僅31.9%,90.9%的首次復發發生於確診後2年內,IgE與嗜酸性球相關性低;類固醇分期治療策略仍待更多研究。

ABPA類固醇治療:病人4週就偷停藥,然後2年內必定復發:—最不嘻嘻的惡性循環。


Restoration of urban agriculture soil by autochthonous fungal biodiversity

Authors: Florio Furno M et al. | Journal: Appl Microbiol Biotechnol | Date: 2026-05-28
DOI: 10.1007/s00253-026-13877-z
TL;DR: 都市農業污染土壤以AspergillusScedosporium等Ascomycota為主,利用真菌聯合體生物復育可顯著降低多環芳香烴(PAH)毒性,部分菌株具biosurfactant生產能力。

Scedosporium在土裡默默分解污染物:—環境版嘻嘻,感染科老敵人有了益用途。


Inflammatory Pseudotumor Due to Actinomycosis Simulating Post-Transplant Lymphoproliferative Disorder

Authors: Lizzetti-Mendoza G et al. | Journal: Transplant Proc | Date: 2026-05-28
DOI: 10.1016/j.transproceed.2026.04.014
TL;DR: 肝臟移植後Actinomyces感染形成偽腫瘤,影像酷似PTLD,引導切片確診後予ampicillin靜脈注射1個月,病灶消退90%,強調移植後非典型肝腫塊鑑別診斷的重要性。

嘻嘻的結局:—Actinomyces造成的「腫瘤」只需抗生素,切片是救命之舉。


Prevalence and clinical correlates of infection in idiopathic inflammatory myopathies: A systematic review and meta-analysis of 14,548 patients

Authors: Yuan G et al. | Journal: Autoimmun Rev | Date: 2026-05-27
DOI: 10.1016/j.autrev.2026.104088
TL;DR: 14,548例發炎性肌病患者感染統合分析:感染盛行率24%,anti-MDA5陽性風險增3.4倍,TMP-SMX預防可降低79%感染風險(OR 0.21),支持高風險者系統性預防投藥。

嘻嘻!TMP-SMX預防在發炎性肌病的感染保護效果顯著,anti-MDA5陽性者更應積極預防。


Real-life performance of a galactomannoprotein-detecting lateral flow immunoassay (AspLFD) in lower respiratory tract and serum specimens for screening pulmonary aspergillosis

Authors: Medina A et al. | Journal: Diagn Microbiol Infect Dis | Date: 2026-05-22
DOI: 10.1016/j.diagmicrobio.2026.117477
TL;DR: AspLFD側流免疫分析臨床實際應用敏感度78.1%、特異度80.9%,與Platelia galactomannan表現相當,非BAL呼吸道檢體亦可適用,適合床邊快篩。

嘻嘻!不需ELISA儀器的側流試紙,臨床準確率不輸Platelia,便利性大加分。


Candida (Candidozyma) auris in pediatric population: risk factors, clinical presentation, and outcomes

Authors: Nascimento BCM et al. | Journal: J Mycol Med | Date: 2026-04-29
DOI: 10.1016/j.mycmed.2026.101626
TL;DR: Candidozyma auris兒科系統性回顧(110例):血流感染佔93.6%,fluconazole耐藥率60.6%,echinocandin療效最佳,死亡率39.1%,早產兒風險最高。

不嘻嘻:—兒童C. auris死亡率近四成,多重抗藥加上診斷困難,兒科ICU的真實噩夢。


Prevalence of Drug-Resistant Mycobacterium tuberculosis in Rural Communities of Vhembe District, South Africa

Authors: Mashilo MS et al. | Journal: Adv Exp Med Biol | Date: 2026
DOI: 10.1007/978-3-032-24254-9_6
TL;DR: 南非Vhembe農村DR-Mycobacterium tuberculosis盛行率2.3%,治療成功率僅20.6%,同時面臨NTM及HIV高共感染率,藥物可近性與後續追蹤仍是主要瓶頸。

不嘻嘻:—20%的治療成功率讓人心涼,南非農村TB控制任重道遠。


Rapid detection of Mycobacterium tuberculosis based on aptamer modified surface-enhanced Raman scattering biosensors

Authors: Liu X et al. | Journal: Spectrochim Acta A Mol Biomol Spectrosc | Date: 2026-05-25
DOI: 10.1016/j.saa.2026.128122
TL;DR: 雙aptamer修飾SERS生物感測器偵測Mycobacterium tuberculosis MPT64抗原:檢測下限20 fg/mL,25份血清樣本敏感度與特異度均達100%,潛力有待規模化臨床驗證。

嘻嘻!aptamer + SERS = 100%敏感度,但只有25個樣本,期待大規模臨床驗證。


Quantifying US healthcare provider preferences for the treatment of post-transplant cytomegalovirus infection using a discrete choice experiment

Authors: Raglow Z et al. | Journal: Curr Med Res Opin | Date: 2026-05-28
DOI: 10.1080/03007995.2026.2676335
TL;DR: 301名美國醫療人員調查:移植後CMV治療首要考量為病毒清除率(26.4%),其次為骨髓抑制風險(17.3%)及藥物交互作用(16.6%),感染科專家尤重病毒清除。

大家都想要CMV清除快又不壓骨髓的藥:—現實是魚與熊掌,不嘻嘻。


Cryptococcus neoformans invasion of the orbital compartment and periocular spaces following intracerebral infection in mice

Authors: Munzen ME et al. | Journal: iScience | Date: 2026 Jun 19
DOI: 10.1016/j.isci.2026.115973
TL;DR: 小鼠 intracerebral infection 後 7 dpi,C. neoformans H99 較 cap59 有更高 brain fungal burden、hydrocephalus 與 cryptococcoma,並可侵入 orbital compartment,可能影響 relapse。

不嘻嘻C. neoformans 連眼眶都想巡房。


🟢 One Health / Zoonoses

Project ODIN: advancing environmental genomic surveillance for public health across sub-Saharan Africa

Authors: Baker B et al. | Journal: Lancet Microbe | Date: 2026-05-28
DOI: 10.1016/j.lanmic.2026.101426
TL;DR: Project ODIN整合宏基因體學與移動式實驗室,在撒哈拉以南非洲建立多病原近即時環境監測體系,強化One Health疫情整備、病原偵測及抗藥性監控。

嘻嘻!歐非攜手以宏基因體學監控One Health威脅,Lancet Microbe加持,格局很大。


A high-resolution, US-scale digital similar of interacting livestock, wild birds, and human ecosystems for multihost epidemic spread

Authors: Adiga A et al. | Journal: Proc Natl Acad Sci U S A | Date: 2026-05-28
DOI: 10.1073/pnas.2507074123
TL;DR: 建構美國規模畜牧、野鳥與人類互動的高解析度數位雙胞胎(FIELD),識別H5N1高風險熱點,顯示高農業密度區與人口稠密區重疊為人畜共通傳播的最大隱患。

嘻嘻!數位雙胞胎模擬H5N1傳播熱點,這種大規模跨物種整合建模正是One Health所需。


Maternal antibody-mediated elimination of a Puumala hantavirus outbreak in a bank vole colony

Authors: Drewes S et al. | Journal: PLoS Pathog | Date: 2026-05-29
DOI: 10.1371/journal.ppat.1013693
TL;DR: 實驗室bank vole群落Puumala hantavirus意外爆發,利用母源抗體(MatAb)保護期(40天)長於病毒環境存活時間的特性,制定分批配對方案成功清除病毒。

嘻嘻!用母源抗體清除漢他病毒,優雅的解決方案,可做其他嚙齒類病原清除的藍本。


Pulmonary echinococcosis caused byG8 in a white-tailed deer (), Pennsylvania, USA, 2026

Authors: Garrett KB et al. | Journal: One Health | Date: 2026-05-15
DOI: 10.1016/j.onehlt.2026.101446
TL;DR: 美國賓州獵殺白尾鹿肺部發現Echinococcus G8造成的囊狀包蟲病,確認白尾鹿為美國東部可行的中間宿主,包蟲病版圖持續向東部擴張。

不嘻嘻:—包蟲病版圖東擴至賓州,獵人與野生動物管理員需提高警覺。


Culture-based characterization of the respiratory mycobiota and antifungal resistance in bottlenose dolphins under human care

Authors: Garcia-Bustos V et al. | Journal: One Health | Date: 2026-05-16
DOI: 10.1016/j.onehlt.2026.101439
TL;DR: 首次評估圈養海豚呼吸道真菌群落:Aspergillus屬最常見,發現azole耐藥(含多重耐藥)菌株,且與抗真菌藥物使用史相關,強調人類管理環境對海洋哺乳動物的抗藥選擇壓力。

不嘻嘻:—海豚的Aspergillus也有azole耐藥性,抗真菌藥物壓力連海豚都逃不掉。


Impacts of meteorological factors on zoonotic infections in domestic cat and dog populations: A scoping review of international evidence

Authors: Hobson SJ et al. | Journal: One Health | Date: 2026-05-14
DOI: 10.1016/j.onehlt.2026.101442
TL;DR: 系統性綜述:高溫與多種蟲媒感染正相關,降雨量與鉤端螺旋體病增加相關;氣候變遷預期加劇家貓狗人畜共通感染風險,但地理與病原特異性差異大。

氣候變遷讓寵物成為人畜共通感染放大器,不嘻嘻的全球暖化附帶效應。


Mpox knowledge and perception in Africa: a systematic review and meta-analysis

Authors: Cheuyem FZL et al. | Journal: BMC Public Health | Date: 2026-05-28
DOI: 10.1186/s12889-026-27872-6
TL;DR: 38項研究、23,648人統合分析:非洲Mpox知識充足率僅43%,中非最低(19%),一般民眾知識嚴重不足,需差異化衛教策略以強化疫情防控。

不嘻嘻:—Mpox在非洲肆虐,卻有近六成民眾知識不足,防疫最脆弱的環節是認知。


A Single Amino Acid Substitution in CspA Increases Germination Sensitivity and Broadens Bile Salt Germinant Specificity in Clostridioides difficile Spores

Authors: Roseiro I et al. | Journal: Environ Microbiol | Date: 2026-Jun
DOI: 10.1111/1462-2920.70332
TL;DR: Clostridioides difficile RT033株CspA R1036I突變使孢子對膽鹽的發芽敏感度上升且範圍擴大,解釋其動物宿主適應性及社區型CDI的潛在動物源頭傳播機制。

不嘻嘻:—一個點突變讓C. difficile更適應動物宿主,社區型CDI的動物-人傳播又多了拼圖。


Molecular prevalence, genomic characterization, and zoonotic potential of novel paramyxovirus and hepacivirus in Alexandromys fortis, Republic of Korea

Authors: Pangestu HS et al. | Journal: Vet Res | Date: 2026-05-28
DOI: 10.1186/s13567-026-01777-z
TL;DR: 韓國蘆葦田鼠(Alexandromys fortis)中發現新型paramyxovirus(Pyeongtaek Alexandromys paramyxovirus)及Hepacivirus J,機器學習評估其具有一定人畜共通傳播潛力。

韓國田鼠又藏了新病毒,不嘻嘻:—東亞嚙齒類是病毒庫這件事持續被驗證。


First report and genomic characterization of an mcr-10.1-carrying Enterobacter kobei strain isolated from a domestic kitchen sink in China

Authors: Liu X et al. | Journal: BMC Microbiol | Date: 2026-05-28
DOI: 10.1186/s12866-026-05205-2
TL;DR: 中國廚房水槽首現攜帶mcr-10.1的Enterobacter kobei:雖表現型仍對colistin敏感,但subinhibitory濃度可上調mcr-10.1表現,凸顯家庭環境colistin耐藥基因的隱性傳播風險。

不嘻嘻:—廚房水槽潛藏colistin耐藥基因,表現型敏感的「隱形抗藥」最難被察覺。


🟡 Food Security / Food Safety

A Comprehensive Review of Biomimicry in Food: Biomimetic Foods, Food Processing, Food Packaging, Food Freezing, and Food Quality Inspection

Authors: Liu Y et al. | Journal: Compr Rev Food Sci Food Saf | Date: 2026-Jul
DOI: 10.1111/1541-4337.70491
TL;DR: 綜述仿生技術在食品五大領域的應用:仿生食品(植物/細胞培養肉)、加工(機器人、3D列印)、包裝(超疏水、抗菌表面)、冷凍控制(抗凍蛋白)及品質檢測(仿生感官系統)。

嘻嘻!仿生技術橫跨食品全產業鏈,培養肉到抗凍蛋白都有,食品科學的大圖景。


Rational fabrication of molecularly imprinted polymers based ratiometric fluorescence sensing platform with aggregation-induced emission effect for visual detection of 6PPD-Q in aquatic products

Authors: Li W et al. | Journal: Food Chem | Date: 2026-05-25
DOI: 10.1016/j.foodchem.2026.149806
TL;DR: 以分子印跡聚合物結合比率螢光感測平台偵測水產品中的輪胎抗氧化劑6PPD-Q,檢測下限3.0 ng/mL,回收率95.5–108.0%,具現場快速視覺化檢測潛力。

嘻嘻!輪胎污染物的快速檢測工具問世,食品安全監測範圍再擴大。


Membrane-protected carboxylated COF-based micro-SPE coupled with HPLC-MS/MS for simultaneous determination of 16 heterocyclic aromatic amines in Cantonese bakery

Authors: Zhu K et al. | Journal: Food Chem | Date: 2026-05-25
DOI: 10.1016/j.foodchem.2026.149808
TL;DR: 以羧基化共價有機框架(COF)建立膜保護微固相萃取法,同時測定廣東烘焙食品中16種雜環胺(HAA),檢測下限0.04–1.39 μg/kg,回收率72.6–118.7%。

廣東烘焙食品的致癌物HAA檢測再升級,嘻嘻(對食安監測),但知道太多也令人不安。


Spermine suppresses-induced macrophage innate immune responses via inhibition of the cGAS-STING and TLR4 pathways

Authors: Wang X et al. | Journal: mBio | Date: 2026-05-29
DOI: 10.1128/mbio.00846-26
TL;DR: Spermine透過促進細菌DNA B→Z構型轉換抑制cGAS-STING活化,並透過TLR4路徑,雙重降低巨噬細胞對Salmonella Typhimurium的先天免疫反應,使胞內菌存活增加。

Salmonella讓宿主polyamine下降以躲避免疫:—不嘻嘻,細菌免疫逃脫的新機制讓人頭皮發麻。


Intense Pulsed Light Treatment for Reducing Escherichia coli and Salmonella on Fresh-Cut Romaine Lettuce and Its Effects on Product Quality

Authors: Gyawali R et al. | Journal: J Food Sci | Date: 2026-Jun
DOI: 10.1111/1750-3841.71146
TL;DR: 強脈衝光處理生菜可減少Escherichia coli 4.03 log CFU/cm²及Salmonella Typhimurium 4.47 log CFU/cm²,不影響質地與葉綠素,可作為生鮮蔬菜的非加熱去污技術。

嘻嘻!強脈衝光殺菌葉菜類,4個對數減少量又不影響質地,食品安全技術新選項。


Study on the Boundary Growth Model of Burkholderia gladioli pv. cocovenenans

Authors: Li S et al. | Journal: J Food Prot | Date: 2026-05-27
DOI: 10.1016/j.jfp.2026.100823
TL;DR: 建立Burkholderia gladioli pv. cocovenenans(bongkrekic acid產毒菌)在pH、NaCl濃度及溫度影響下的生長邊界logistic迴歸模型,concordance index達0.944,可用於食品安全風險評估。

嘻嘻(對預防中毒):—bongkrekic acid產毒菌終於有了生長預測模型,食品安全監控更精準。


Effects and mechanisms of different organic manure on minimizing cadmium concentrations in rice grains

Authors: Liu Y et al. | Journal: Int J Phytoremediation | Date: 2026-05-29
DOI: 10.1080/15226514.2026.2677688
TL;DR: 不同來源有機肥對鎘污染土壤中水稻的鎘積累有差異影響:鵝糞(GM)與蚓糞(EM)顯著減少水稻鎘吸收,雞糞(CM)過量則增加重金屬生物累積風險。

不嘻嘻:—鎘污染水稻靠有機肥種類選擇來控制,但土壤重金屬污染仍是系統性難題。


Food-Type-Driven Detection, Concentration Profiling and Probabilistic Risk Mapping of Pb, Cd and Hg in Foods

Authors: Sirhan A et al. | Journal: Biol Trace Elem Res | Date: 2026-05-29
DOI: 10.1007/s12011-026-05165-8
TL;DR: 2,114份食品重金屬監測:汞(Hg)偵測率84.5%(以海鮮為主),大量攝取海鮮時汞危害商數超標率達64%;香料/草藥鎘含量偏高,需加強分類風險監測框架。

不嘻嘻:—大量吃海鮮者汞超標風險高達64%,重金屬污染的食品安全警訊仍未解決。


Biocontrol of Fusarium culmorum and enhanced wheat seedling growth by Streptomyces sp. D15 from Algerian steppe soil: performance and genome analysis

Authors: Toumatia O et al. | Journal: World J Microbiol Biotechnol | Date: 2026-05-29
DOI: 10.1007/s11274-026-04965-3
TL;DR: 阿爾及利亞草原土壤分離的Streptomyces lavendofoliae D15可有效抑制Fusarium culmorum(疾病嚴重度降87%),同時促進小麥幼苗生長(芽長增67%),提供永續農業生防選項。

嘻嘻!用Streptomyces對付Fusarium,天然生物防治比化學農藥更eco-friendly,糧食安全好消息。


SiOshell-protected magnetic fluorescent tag for on-site ultrasensitive immunodetection of foodborne viruses

Authors: Chen Y et al. | Journal: Mikrochim Acta | Date: 2026-05-29
DOI: 10.1007/s00604-026-08149-6
TL;DR: SiO₂殼保護磁性量子點螢光標記的側流免疫分析同時偵測norovirus和adenovirus:檢測下限達pg/mL級,75份臨床糞便樣本靈敏度>92%、特異度100%,優於傳統金標記LFA。

嘻嘻!一次偵測兩種食源性病毒,糞便複雜基質難題被SiO₂保護層克服,現場快篩更可靠。


Bilobalide attenuates Salmonella typhimurium virulence by repressing the quorum sensing and type III secretion system effectors

Authors: Wang R et al. | Journal: Phytomedicine | Date: 2026-05-22
DOI: 10.1016/j.phymed.2026.158330
TL;DR: 銀杏提取物bilobalide透過與Salmonella typhimurium QseB直接結合,抑制quorum sensing及T3SS效應蛋白,顯著降低biofilm形成,小鼠模型中並強化抗生素療效。

嘻嘻!銀杏成分bilobalide讓Salmonella的毒力基因沉默,植物天然抗毒力策略想像空間大。


資料來源:PubMed (articles retrieved 2026-05-30)