Daily Journal Digest — 2026-05-05¶

過去 24 小時新增：Transplant ID × 30、One Health × 10、Food Security × 10，共 50 篇。

🔴 Transplant & Opportunistic Infections¶

Longitudinal TCR repertoire profiling predicts refractory cytomegalovirus reactivation after haploidentical hematopoietic stem cell transplantation¶

Authors: Yuan H et al. | Journal: Virology journal | Date: 2026 May 02
DOI: 10.1186/s12985-026-03181-7
TL;DR: Haplo-HSCT 後 CMV 反覆活化達 48%；TCR clonality 升高、多樣性下降可預測難治型反應。
評: 嘻嘻 — 用 TCR 譜系預測誰會被 CMV 纏上，免疫學的算命終於走進臨床。

Retrospective analysis of the epidemiological characteristics, risk factors, survival rate, and drug resistance of candidemia and construction of a logistic regression prediction model (2013-2024)¶

Authors: Xu Z et al. | Journal: BMC infectious diseases | Date: 2026 May 02
DOI: 10.1186/s12879-026-13510-4
TL;DR: 雲南 12 年 candidemia 分析；amphotericin B 與 echinocandin 對所有 Candida 仍 100% 有效。
評: 嘻嘻 — 至少在雲南 echinocandin 還沒被打趴，這年頭已是奢侈。

The gut metabolite arachidonic acid alleviates intestinal injury induced by a Toxoplasma gondii strain isolated from a wild rodent¶

Authors: Yuan H et al. | Journal: Parasites & vectors | Date: 2026 May 02
DOI: 10.1186/s13071-026-07389-y
TL;DR: 野生鼠源 T. gondii 重創腸道屏障；補充花生四烯酸可緩解病灶與腦囊蟲負擔。
評: 嘻嘻 — 一個代謝物就能緩解寄生蟲腸炎，廚房裡的脂肪酸竟是隱藏英雄。

Global incidence rates of invasive fusariosis: a systematic review and meta-analysis¶

Authors: Sarhan AA et al. | Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases | Date: 2026 May 01
DOI: 10.1016/j.ijid.2026.108760
TL;DR: 全球首次 invasive fusariosis 流行病學估計：HSCT 8.87 / 1000、肺移植族群最高。
評: 不嘻嘻 — Fusarium 對任何治療都笑而不語，這數字提醒大家先預防比較實在。

Polyamines as Gatekeepers of Virus Replication and Central Nervous System Homeostasis¶

Authors: Stacey SP et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Apr 14
DOI: 10.3390/pathogens15040422
TL;DR: 多胺代謝是嗜神經病毒（CMV、Zika、polio）共通依賴；可作廣效抗病毒新標的。
評: 嘻嘻 — 鎖定宿主代謝物的廣效抗病毒思路，比追著病毒跑似乎更有勝算。

Kidney Transplant Recipients: Viral Infections and Malignancies¶

Authors: Damian C et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Apr 05
DOI: 10.3390/pathogens15040390
TL;DR: 215 名腎移植住院者：病毒陽性 16.7%，與 AKI（aOR 3.0）、慢性移植腎功能不良獨立相關。
評: 不嘻嘻 — 又一篇證實病毒+癌症+AKI 三件套，腎臟科醫師沒一天好過。

Antimicrobial Drug Prophylaxis for Recurrent Ocular Toxoplasmosis¶

Authors: Keshavarz T et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Apr 04
DOI: 10.3390/pathogens15040388
TL;DR: TMP-SMX 為眼部弓形蟲復發預防最常用藥；5 年復發率最低 9.1%、副作用 7.9%。
評: 嘻嘻 — 老藥長用還是有效，眼科醫師的 TMP-SMX 信仰再添一筆。

Bronchoalveolar Lavage Fluid Cytomegalovirus DNA Load as a Predictor of Mortality in AIDS Patients with Pulmonary Infections: A Retrospective Cohort Study¶

Authors: Yang J et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Apr 01
DOI: 10.3390/pathogens15040377
TL;DR: AIDS 肺感染者 BALF CMV DNA >10,000 copies/mL 是 90 天死亡獨立預測因子（aOR 3.78）。
評: 不嘻嘻 — 血漿測不到肺裡的 CMV 才是重點，又一個提醒「驗對檢體」的故事。

Seroprevalence of IgG Antibodies Against Toxoplasma gondii in HIV-Infected and Non-Infected Population in Iquitos, Peru¶

Authors: Faustino M et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Apr 01
DOI: 10.3390/pathogens15040374
TL;DR: 秘魯亞馬遜地區 HIV+ 弓形蟲 IgG 血清陽性率 91.3%，潛在再活化風險極高。
評: 不嘻嘻 — 91% 血清陽性等於遲早會見到再活化，神經系統合併症在等著。

Cytomegalovirus Infection of the Anterior Segment: Corneal Endotheliitis and Secondary Glaucoma¶

Authors: Liu F et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Mar 31
DOI: 10.3390/pathogens15040371
TL;DR: CMV 前段眼感染可致角膜內皮炎與續發青光眼；前房液 PCR 為金標準，ganciclovir 為主軸。
評: 不嘻嘻 — CMV 連免疫健全的眼睛都不放過，眼科 PCR 該列為常規了。

Comparison of Serological Methods for the Diagnosis of Toxoplasmosis in Pregnant Women¶

Authors: Rodrigues NJL et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Mar 29
DOI: 10.3390/pathogens15040363
TL;DR: 孕婦弓形蟲血清學：IFA / MAT IgG 敏感度高於 CMIA；建議互補使用以提升產前診斷準確度。
評: 嘻嘻 — 老派 IFA 沒被自動化打敗，手工活還是有它的細膩。

New Models for the Study of Ocular Toxoplasmosis. Comment on Ashander et al. Human Retinal Organoid Model of Ocular Toxoplasmosis. Pathogens 2025, 14, 286¶

Authors: Bruschi F et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Mar 27
DOI: 10.3390/pathogens15040357
TL;DR: 視網膜類器官為眼部弓形蟲研究提供新模型；本文補充原作評論觀點。
評: 嘻嘻 — 類器官接管視網膜研究，動物實驗在角落哀嚎。

Toxoplasma gondii and a Cancer Biology Dichotomy: A Systematic Review of Experimental Studies of Its Antitumor and Pro-Tumor Effects¶

Authors: Jhandi S et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Mar 26
DOI: 10.3390/pathogens15040351
TL;DR: 54 篇實驗綜述：急性 T. gondii 感染多顯抗腫瘤效應，慢性感染則偏促癌。
評: 嘻嘻 — 寄生蟲意外成為抗癌候選人，演化的反差萌再次上線。

Parasites as Modulators of Angiogenesis: Implications for Vascular Biology and Pathogenesis¶

Authors: Rodríguez T et al. | Journal: Pathogens (Basel, Switzerland) | Date: 2026 Mar 25
DOI: 10.3390/pathogens15040347
TL;DR: 原蟲與蠕蟲操控宿主血管新生以利存活，其分泌因子或可成為慢性退化疾病療法。
評: 嘻嘻 — 寄生蟲分泌物轉用治癌，醫學版的廢物利用。

National Surveillance of Candidemia in the Czech Republic: Preliminary Results from the 2023 Multicentre Study¶

Authors: Lysková P et al. | Journal: Mycopathologia | Date: 2026 May 04
DOI: 10.1007/s11046-026-01076-3
TL;DR: 捷克 2023 candidemia 監測：C. albicans 40.6%；C. parapsilosis fluconazole 抗藥達 16.9%。
評: 不嘻嘻 — C. parapsilosis 抗 fluconazole 已破 17%，azole 在退場路上。

Epidemiology, Risk Factors, and Routine Blood Biomarkers of Aspergillosis in Cancer Patients in Jiangxi, China¶

Authors: Bilal H et al. | Journal: Infection and drug resistance | Date: 2026
DOI: 10.2147/IDR.S599801
TL;DR: 江西癌症 aspergillosis 354 例；類固醇、化療、高血糖為獨立風險因子，A. fumigatus 佔 88%。
評: 不嘻嘻 — 老三樣（類固醇、化療、高血糖）+ Aspergillus，劇本永遠是同一套。

Interpretable SVM Model for Predicting CMV Infection in Seropositive Kidney Transplant Recipients: A Single-Center Retrospective Study¶

Authors: Zhong G et al. | Journal: Infection and drug resistance | Date: 2026
DOI: 10.2147/IDR.S577857
TL;DR: 腎移植 CMV R+ 患者 SVM 預測模型 AUC 0.821；CD4 / CD8 T 細胞數為最重要預測因子。
評: 嘻嘻 — 機器學習加 SHAP 把 CMV 預防策略推向個人化，臨床決策更有底。

Molecular detection of Toxoplasma gondii in Amblyomma gervaisi ticks infesting monitor lizards (Varanus bengalensis)¶

Authors: Naeem M et al. | Journal: Experimental & applied acarology | Date: 2026 May 02
DOI: 10.1007/s10493-026-01139-6
TL;DR: 巴基斯坦監視蜥身上 Amblyomma gervaisi 蜱 11% 檢出 T. gondii，蜱可能參與爬行類間傳播。
評: 嘻嘻 — 蜥蜴+蜱+弓形蟲三方亂鬥，One Health 故事再添一頁。

Bilateral necrotising retinitis caused by cytomegalovirus in an immunocompetent host: A case report¶

Authors: Murugan SB et al. | Journal: Tropical doctor | Date: 2026 May 04
DOI: 10.1177/00494755261445972
TL;DR: 31 歲免疫健全男性發生雙側 CMV 視網膜壞死；ganciclovir 玻璃體注射後改善。
評: 不嘻嘻 — 免疫正常照樣中標，CMV 又一次提醒我們別把它當小角色。

Discovery of New Pyrazolone Derivatives for Treating Invasive Fungal Infections by Iron Homeostasis Disruption¶

Authors: Zou P et al. | Journal: Journal of medicinal chemistry | Date: 2026 May 04
DOI: 10.1021/acs.jmedchem.6c00557
TL;DR: 新型 pyrazolone 衍生物 D2 對 Cryptococcus 與 C. glabrata MIC 達 0.0001 µg/mL；以鐵恆定為機制。
評: 嘻嘻 — 亞奈克 MIC 加雙效（殺菌+抑毒力），抗黴菌藥物難得有點好消息。

Innate immune profiling reveals a specific reduction of CD57+CD62L+CD161+ NK cells in CMV-positive males with hypertension¶

Authors: Wang X et al. | Journal: Frontiers in immunology | Date: 2026
DOI: 10.3389/fimmu.2026.1749702
TL;DR: CMV 陽性高血壓男性特定 NK 亞群（CD57+CD62L+CD161+ KLRC2high adaptive）顯著減少。
評: 嘻嘻 — 高血壓的免疫學新故事，CMV 又被點名擔任主謀。

Authors: Boodwa-Ko D et al. | Journal: bioRxiv : the preprint server for biology | Date: 2026 Apr 22
DOI: 10.64898/2026.04.21.719979
TL;DR: 新發現 Cxt2 與 Cxt1 共同負責 Cryptococcus 木糖添加；補上糖蛋白合成缺口。
評: 嘻嘻 — 隱球菌的糖衣內幕又揭一層，未來抗毒力策略多了個靶。

Myeloid Cell States in Influenza-Associated Pulmonary Aspergillosis Are Shaped by Iron Overload and Metabolic Reprogramming¶

Authors: Grau MS et al. | Journal: bioRxiv : the preprint server for biology | Date: 2026 Apr 25
DOI: 10.64898/2026.04.22.720189
TL;DR: 流感後 Aspergillus 共感染：肺髓系細胞鐵負荷升高、代謝重編，吞噬與抗病毒功能皆受抑。
評: 不嘻嘻 — 流感+黴菌雙打，宿主免疫被鐵壓垮，重症 ICU 的惡夢有了分子註解。

scSketch: Interactive Sketch-based Trajectory Exploration and Pathway-Aware Analysis of Single-Cell Data¶

Authors: Temirbek A et al. | Journal: bioRxiv : the preprint server for biology | Date: 2026 Apr 23
DOI: 10.64898/2026.04.16.718997
TL;DR: scSketch：互動式單細胞軌跡探索工具；應用於 CMV 感染口腔角質細胞揭示干擾素與自噬反應。
評: 嘻嘻 — 滑鼠畫一畫就能跑路徑分析，bioinformatics 終於對人類友善一點。

A SuperSelective primer-based real-time PCR Platform for hypersensitive detection of azole heteroresistance in Cryptococcus neoformans¶

Authors: Pawar S et al. | Journal: bioRxiv : the preprint server for biology | Date: 2026 Apr 24
DOI: 10.64898/2026.04.23.720376
TL;DR: SSP-PCR 平台可在 1:10,000 比例檢出 Cryptococcus ERG11 抗 azole 突變，靈敏度極高。
評: 嘻嘻 — 可以從一堆野生型裡撈出單一突變株，藥敏監測進入分子時代。

Toxoplasma gondii associates with human Benign Prostatic Hyperplasia and induces prostatic hyperplasia and accompanying urinary dysfunction in mice¶

Authors: Stanczak EF et al. | Journal: bioRxiv : the preprint server for biology | Date: 2026 Apr 24
DOI: 10.64898/2026.04.23.720409
TL;DR: 弓形蟲血清陽性與男性 BPH 及腺體結節相關；小鼠模型亦再現排尿功能異常。
評: 嘻嘻 — 攝護腺肥大背後居然有寄生蟲？老男人們：別再只怪 testosterone 了。

Invasive pericardial and pulmonary aspergillosis by uncommon Aspergillus species in anti-interferon-γ autoantibody-associated immunodeficiency: a case report¶

Authors: Tang J et al. | Journal: Frontiers in medicine | Date: 2026
DOI: 10.3389/fmed.2026.1760017
TL;DR: 抗 IFN-γ 自體抗體免疫缺陷致心包與肺侵襲性麴菌病；多線抗黴後仍多重器官衰竭死亡。
評: 不嘻嘻 — 罕見免疫缺陷碰罕見麴菌種，連 isavuconazole + amphotericin 都救不回。

The Peripartum Immune Whiplash: Concomitant Cryptococcosis and Granulomatosis With Polyangiitis¶

Authors: Cartwright T et al. | Journal: Cureus | Date: 2026 Apr
DOI: 10.7759/cureus.106335
TL;DR: 產後 8 週女性 pulmonary cryptococcosis 同時合併 GPA；血管炎被感染症狀掩蓋延誤診斷。
評: 不嘻嘻 — 兩個罕見病同時發生，這人生劇本太狠了。

Optimization of Antifungal 1,5-Diaryl-Pyrazole Acetyl-CoA Synthetase Inhibitors¶

Authors: Propp JP et al. | Journal: ACS omega | Date: 2026 Apr 28
DOI: 10.1021/acsomega.5c13157
TL;DR: AR-12 衍生物對 Candida、Cryptococcus、Aspergillus ACS 抑制活性與選擇性提升；尚需動物驗證。
評: 嘻嘻 — 抗黴新標的 ACS 候選分子持續進化，雖然離臨床還有距離。

🟢 One Health / Zoonoses¶

Enhanced Immunogenicity and Dose-Sparing Efficacy of SelfAmplifying RNA Vaccines Against Seasonal Influenza Across Subtypes¶

Authors: Huang M et al. | Journal: Emerging microbes & infections | Date: 2026 May 04
DOI: 10.1080/22221751.2026.2668752
TL;DR: Self-amplifying RNA 三價流感疫苗單劑 0.1 µg 即引發抗 IBV 完全保護；mRNA 平台僅 14% 存活。
評: 嘻嘻 — saRNA 在低劑量、抗 B 流上完勝傳統 mRNA，下一代疫苗有戲。

Engineered Bispecific Antibodies Achieve Broad and Potent Protection Against Multiple Ebolavirus Species¶

Authors: Zhou J et al. | Journal: Emerging microbes & infections | Date: 2026 May 04
DOI: 10.1080/22221751.2026.2668755
TL;DR: 三種 bsAb 平台中 IgG-ScFv 對 EBOV / SUDV / BDBV 中和力與小鼠保護最佳。
評: 嘻嘻 — 一抗對付多種伊波拉病毒，疫情不再挑單一品系。

mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines elicits distinct antibody epitope signatures¶

Authors: Cohen AA et al. | Journal: Cell reports | Date: 2026 Apr 30
DOI: 10.1016/j.celrep.2026.117335
TL;DR: mRNA 編碼 mosaic-8 RBD 四聚體誘發更廣交叉中和與更佳 T 細胞反應，適合泛冠狀疫苗。
評: 嘻嘻 — Mosaic-8 從蛋白搬到 mRNA，跨株保護性又升一級。

A Comprehensive Review of Vaccine Technologies for Pandemic Preparedness Against Highly Pathogenic Avian Influenza¶

Authors: Rather MA et al. | Journal: Reviews in medical virology | Date: 2026 May
DOI: 10.1002/rmv.70161
TL;DR: 回顧家禽 HPAI 疫苗平台限制，提出 mRNA / 載體 / 嵌合等下一代策略以備人畜共通大流行。
評: 不嘻嘻 — 一篇 review 提醒我們：禽流感疫苗仍跟不上病毒演化。

Niclosamide Inhibits the Replication of Highly Pathogenic Avian Influenza A (H5Nx) Viruses and Antiviral-Resistant Mutants¶

Authors: Chiba S et al. | Journal: Antiviral research | Date: 2026 May 01
DOI: 10.1016/j.antiviral.2026.106421
TL;DR: Niclosamide（FDA 抗蠕蟲藥）對 H5N1/H5N6/H5N8 IC50 0.68–1.40 µM；對 baloxavir、favipiravir 抗藥株仍有效。
評: 嘻嘻 — 老藥新用又一例，禽流感應對藥庫多了一條備胎。

Climate change, planetary health and education in Africa - Some case studies and perspectives¶

Authors: Filho WL et al. | Journal: One health (Amsterdam, Netherlands) | Date: 2026 Jun
DOI: 10.1016/j.onehlt.2026.101406
TL;DR: 非洲大學「planetary health」教學罕見；建議在公衛課程中明確納入此主題。
評: 不嘻嘻 — 連名詞都還沒普及，氣候健康教育之路漫長。

Importation risks and local transmission of Japanese encephalitis virus in Taiwan¶

Authors: Fan YC et al. | Journal: One health (Amsterdam, Netherlands) | Date: 2026 Jun
DOI: 10.1016/j.onehlt.2026.101422
TL;DR: 台灣過去 67 年至少 6 次 JEV 移入；GI 亞群 2018 後出現帶 E-V441I 突變的新優勢株。
評: 不嘻嘻 — 日本腦炎在台灣已落地生根並悄悄演化，疫苗株更新需考慮。

Authors: Haddad A et al. | Journal: One health (Amsterdam, Netherlands) | Date: 2026 Jun
DOI: 10.1016/j.onehlt.2026.101420
TL;DR: 法國布列塔尼養豬業者 2023-24 流感疫苗接種率僅 14%，3 成不知政府推薦。
評: 不嘻嘻 — 高風險族群連「有推薦」都不知道，人畜共通預防工作還沒走完第一步。

One Health in the public mind: Narrative constructions of zoonotic spillovers¶

Authors: Shanahan EA et al. | Journal: One health (Amsterdam, Netherlands) | Date: 2026 Jun
DOI: 10.1016/j.onehlt.2026.101411
TL;DR: 澳洲沿岸民眾僅 14% 在描述 zoonotic spillover 時涵蓋人/動物/環境三面向。
評: 不嘻嘻 — One Health 在大眾腦中還是只剩「人」，宣傳的路還很長。

Health Literacy, Service Readiness, and Community Reinforcement of Rabies-Prevention Behaviors in Rural Thailand¶

Authors: Khumkaew J et al. | Journal: International journal of environmental research and public health | Date: 2026 Apr 17
DOI: 10.3390/ijerph23040515
TL;DR: 泰國農村狂犬病防治：健康識能與社區增強行為強相關；服務面需透過社區傳播強化。
評: 嘻嘻 — SEM 證實「衛教 + 社區」才是防狂犬王道，光靠醫院推不動。

🟡 Food Security / Food Safety¶

Impact of natural antimicrobials on survival behavior and cell morphology of acid-stressed pathogens in ready-to-eat rice¶

Authors: Kim NH et al. | Journal: International journal of food microbiology | Date: 2026 Apr 30
DOI: 10.1016/j.ijfoodmicro.2026.111826
TL;DR: 酸化即食米加 VERDAD N6 + ε-PL 可加速殺死 E. coli O157:H7；對 B. cereus 孢子幾無作用。
評: 嘻嘻 — 食品科技用天然抑菌劑加上酸化策略，米飯多一層保險。

Flavouring Group Evaluation 82 Revision 2 (FGE.82Rev2): Consideration of epoxides evaluated by JECFA¶

Authors: Castle L et al. | Journal: EFSA journal. European Food Safety Authority | Date: 2026 Apr
DOI: 10.2903/j.efsa.2026.10055
TL;DR: EFSA 重新評估 5 個 epoxide 香料添加物；β-ionone epoxide NOAEL 訂為 39 mg/kg/day。
評: 嘻嘻 — 法規又把香料安全門檻釘得更明確一點。

Diet Cost and Affordability in Queensland: A Two-Year Cross-Sectional Study¶

Authors: Earle R et al. | Journal: International journal of environmental research and public health | Date: 2026 Apr 20
DOI: 10.3390/ijerph23040535
TL;DR: 昆士蘭 2 年調查：健康飲食對原住民家庭仍佔收入 26% 以上，超越 25% 的食物壓力門檻。
評: 不嘻嘻 — 健康吃就是貴，弱勢家庭被結構性綁住。

A Qualitative Study of Maternal and Caregiver Perceptions of Dietary Practices Contributing to Undernutrition Among Children Under Five in Ngqeleni, Eastern Cape¶

Authors: Mto P et al. | Journal: International journal of environmental research and public health | Date: 2026 Apr 11
DOI: 10.3390/ijerph23040482
TL;DR: 南非鄉村孩童營養不良由貧窮、食物不安全、文化餵食習慣與旱情共同形塑。
評: 不嘻嘻 — 結構性貧困加氣候變遷，孩子吃不飽不只是個人選擇。

Improving Health Equity for Spanish-Speaking Latine Communities: Community Priorities, Challenges, and Recommendations¶

Authors: Aguilar-Palma SK et al. | Journal: International journal of environmental research and public health | Date: 2026 Apr 09
DOI: 10.3390/ijerph23040472
TL;DR: 北卡 Latine 社區共識論壇列出 8 項健康公平優先事項，含食物安全與雙語心理服務。
評: 嘻嘻 — 由社群自己訂議題的 CBPR 模式值得借鏡。

Authors: Abasilim OR et al. | Journal: International journal of environmental research and public health | Date: 2026 Apr 03
DOI: 10.3390/ijerph23040458
TL;DR: 美國青少年食物不安全 obesity 風險高 48%；貧困、種族與身體活動有顯著互動效應。
評: 不嘻嘻 — 又是「越窮越胖」的結構性悲劇，吃不飽和吃太胖竟在同一個族群。

Authors: Yaneva G et al. | Journal: International journal of environmental research and public health | Date: 2026 Mar 25
DOI: 10.3390/ijerph23040411
TL;DR: 全球野菇中毒：Amanita amatoxin 仍是致死主因，亞洲與部分歐洲為高發區。
評: 不嘻嘻 — 採菇人請看清楚再吃，這比創業金句還危險。

Genomic characterization of avian pathogenic Escherichia coli and its potential as a marker organism for antimicrobial resistance¶

Authors: Gaonkar PP et al. | Journal: Applied and environmental microbiology | Date: 2026 May 04
DOI: 10.1128/aem.02244-25
TL;DR: 肉雞生產鏈中 APEC 含 ST131 高風險株與共通核心抗藥基因組，可作為 AMR 指標菌。
評: 不嘻嘻 — 雞舍裡的大腸桿菌與環境基因高度相連，農場到餐桌的耐藥傳播鏈再添實證。

Probiotic potential of Lactobacillus acidophilus TMPC 41127 isolated from traditional cheese in inhibiting Salmonella Typhi biofilms and virulence genes¶

Authors: Alizadeh Behbahani B et al. | Journal: Scientific reports | Date: 2026 May 03
DOI: 10.1038/s41598-026-51296-2
TL;DR: Khiki 起司分離的 L. acidophilus TMPC 41127 顯著抑制 S. Typhi 生物膜與毒力基因表現。
評: 嘻嘻 — 起司裡的乳酸菌也能對抗傷寒桿菌，傳統食品的隱藏功用越挖越多。

Antibacterial and antibiofilm activity of a triterpenoid-rich Eucalyptus globulus leaf extract against gram-positive bacteria¶

Authors: Spaggiari C et al. | Journal: Scientific reports | Date: 2026 May 03
DOI: 10.1038/s41598-026-50090-4
TL;DR: 尤加利葉萃取主成分 ursolic / asiatic acid 對 S. pyogenes MIC 2 µg/mL；對 MRSA 亦有抑菌與抗生物膜活性。
評: 嘻嘻 — 桉葉裡的三萜不只防蚊，連 MRSA 都怕，植物化學再立一功。

資料來源：PubMed (articles retrieved 2026-05-05)